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1.14.13.167: 4-nitrophenol 4-monooxygenase

This is an abbreviated version!
For detailed information about 4-nitrophenol 4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.167

Reaction

4-nitrophenol
+
NADPH
+
H+
+
O2
=
1,4-benzoquinone
+
nitrite
+
NADP+
+
H2O

Synonyms

2C4NP 4-monooxygenase, 4-NP/4-NCA monooxygenase, NpcA, para-nitrophenol 4-monooxygenase, PdcA, PNP 4-monooxygenase, pnpA, PnpA1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.167 4-nitrophenol 4-monooxygenase

Systematic Name

Systematic Name on EC 1.14.13.167 - 4-nitrophenol 4-monooxygenase

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SYSTEMATIC NAME
IUBMB Comments
4-nitrophenol,NAD(P)H:oxygen 4-oxidoreductase (4-hydroxylating, nitrite-forming)
Contains FAD. The enzyme catalyses the first step in a degradation pathway for 4-nitrophenol, the oxidation of 4-nitrophenol at position 4 with the concomitant removal of the nitro group as nitrite. The enzyme from the bacterium Pseudomonas sp. strain WBC-3 also catalyses EC 1.14.13.166, 4-nitrocatechol 4-monooxygenase.