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1.14.13.178: methylxanthine N1-demethylase

This is an abbreviated version!
For detailed information about methylxanthine N1-demethylase, go to the full flat file.

Reaction

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Caffeine
+
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O2
+
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NAD(P)H
+
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H+
=
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Theobromine
+
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NAD(P)+
+
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H2O
+
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formaldehyde

Synonyms

ndmA, P450-d

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                EC 1.14.13.1781.14.13.178 methylxanthine N1-demethylase

Reaction

Reaction on EC 1.14.13.178 - methylxanthine N1-demethylase

for references in articles please use BRENDA:EC1.14.13.178

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
caffeine + O2 + NAD(P)H + H+ = theobromine + NAD(P)+ + H2O + formaldehyde
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paraxanthine + O2 + NAD(P)H + H+ = 7-methylxanthine + NAD(P)+ + H2O + formaldehyde
show the reaction diagram
theophylline + O2 + NAD(P)H + H+ = 3-methylxanthine + NAD(P)+ + H2O + formaldehyde
show the reaction diagram