1.14.13.2: 4-hydroxybenzoate 3-monooxygenase

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.2

1.14.13.2

flavin

fad

fluorescens

flavoproteins

isoalloxazine

protocatechuate

3,4-dioxygenase

massey

2,4-dihydroxybenzoate

ballou

c4a-hydroperoxide

3-hydroxybenzoate

gatti

degradation

analysis

Reaction

Synonyms

4-HBA 3-hydroxylase, 4-HBA 3-monooxygenase, 4-HBA-3-hydroxylase, 4-HBMO, 4-hydroxybenzoate 3-hydroxylase, 4-hydroxybenzoate 3-monooxygenase, 4-hydroxybenzoate hydroxylase, 4-hydroxybenzoate monooxygenase, 4-hydroxybenzoic hydroxylase, 4HBA 3-hydroxylase, An_PhhA, BxeA2040, FAD-dependent 4-hydroxybenzoate hydroxylase, fungal 4-hydroxybenzoate 3-hydroxylase, HBH, m-hydroxybenzoate hydroxylase, MobA, NADPH-dependent 4-HBA hydroxylase, ncgl1032, oxygenase, 4-hydroxybenzoate 3-mono-, p-hydroxybenzoate hydroxylase, p-hydroxybenzoate-3-hydroxylase, p-hydroxybenzoic acid hydrolase, p-hydroxybenzoic acid hydroxylase, p-hydroxybenzoic hydroxylase, PaPobA, para-hydroxybenzoate hydroxylase, PHBAD, PHBH, PHBHase, PHBHCn2, phhA, PobA, pobACg, POHBase, Reut_B4006

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.2 4-hydroxybenzoate 3-monooxygenase

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Results	in table
8	Activating Compound
4541	AA Sequence
5	Application
1	CAS Registry Number
22	Cloned(Commentary)
96	Cofactor
17	Crystallization (Commentary)
6	Expression
43	General Information
7	General Stability
88	Inhibitors
17	kcat/KM [mM/s]
13	Ki Value [mM]
88	KM Value [mM]
1	Metals/Ions
27	Molecular Weight [Da]
57	Natural Substrates/ Products (Substrates)
170	Organism
14	Pathway
37	PDB ID
17	pH Optimum
1	pH Range
4	pH Stability
147	Protein Variants
19	Purification (Commentary)
14	Reaction
3	Reaction Type
115	Reference
16	Specific Activity [micromol/min/mg]
5	Storage Stability
208	Substrates and Products (Substrate)
32	Subunits
145	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
19	Temperature Stability [°C]
53	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 1.14.13.2 - 4-hydroxybenzoate 3-monooxygenase

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2,4-Dihydroxybenzoate

Pseudomonas fluorescens

increases the rate of NADP oxidation by 4-hydroxybenzoate, no hydroxylation during subsequent reoxidation by O2

390019

3,4-dihydroxybenzoate

Pseudomonas fluorescens

increases the rate of NADP oxidation by 4-hydroxybenzoate, no hydroxylation during subsequent reoxidation by O2

390019

5-Hydroxypicolinate

Pseudomonas aeruginosa

stimulates rapid oxidation of NADPH

390026

benzoate

Pseudomonas fluorescens

increases the rate of NADP oxidation by 4-hydroxybenzoate, no hydroxylation during subsequent reoxidation by O2

390019

dithiothreitol

Corynebacterium glutamicum

4 mM, slightly increases activity

684641

EDTA

Corynebacterium glutamicum

5 mM or 20 mM, slightly increases activity

684641

additional information

2 entries