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1.14.13.211: rifampicin monooxygenase

This is an abbreviated version!
For detailed information about rifampicin monooxygenase, go to the full flat file.

Reaction

rifampicin
+
NAD(P)H
+
O2
=
2'-N-hydroxyrifampicin
+
NAD(P)+
+
H2O

Synonyms

RIF-O, rifampicin monooxygenase, RifMO, rox

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.211 rifampicin monooxygenase

Substrates Products

Substrates Products on EC 1.14.13.211 - rifampicin monooxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
16-demethylrifamycin W + NAD(P)H + O2
? + NAD(P)+ + H2O
show the reaction diagram
rifampicin + NAD(P)H + O2
2'-N-hydroxyrifampicin + NAD(P)+ + H2O
show the reaction diagram
rifamycin SV + NAD(P)H + O2
? + NAD(P)+ + H2O
show the reaction diagram
additional information
?
-