1.14.13.22: cyclohexanone monooxygenase

This is an abbreviated version!
For detailed information about cyclohexanone monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.22

1.14.13.22

baeyer-villiger

acinetobacter

lactones

bvmos

ncimb

calcoaceticus

cyclohexanol

synthesis

criegee

epsilon-caprolactone

c4a-peroxyflavin

biooxidation

bicyclo3.2.0hept-2-en-6-one

phenylacetone

cyclopentanone

biotechnology

Reaction

Synonyms

Bpro_556, CAMO, CHMO, ChnB, chnB protein, chnB1 protein, CHXON, CMO, cycloalkaone monooxygenase, cyclohexanone 1, 2-mono-oxygenase, cyclohexanone mono-oxygenase, cyclohexanone monooxygenase, cyclohexanone oxygenase, cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming), oxygenase, cyclohexanone mono-

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.22 cyclohexanone monooxygenase

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Results	in table
3	Activating Compound
667	AA Sequence
23	Application
2	CAS Registry Number
33	Cloned(Commentary)
84	Cofactor
5	Crystallization (Commentary)
3	General Information
1	General Stability
37	Inhibitors
30	kcat/KM [mM/s]
11	Ki Value [mM]
102	KM Value [mM]
6	Localization
1	Metals/Ions
16	Molecular Weight [Da]
51	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
171	Organism
1	Oxidation Stability
5	Pathway
14	PDB ID
15	pH Optimum
4	pH Range
6	pH Stability
59	Protein Variants
32	Purification (Commentary)
23	Reaction
11	Reaction Type
102	Reference
2	Source Tissue
28	Specific Activity [micromol/min/mg]
10	Storage Stability
491	Substrates and Products (Substrate)
16	Subunits
65	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
15	Temperature Stability [°C]
72	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.14.13.22 - cyclohexanone monooxygenase

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-18°C, crude homogenates, negligible loss of activity, 2 months

Acinetobacter calcoaceticus

438991

-20°C, more than 1 year

-20°C, stable

-25�C, pH 7.1

25°C, 1 M sodium sulfate, half-life 1 week

Acinetobacter calcoaceticus

438989

25°C, half-life 1 day

Acinetobacter calcoaceticus

438989

4°C, in presence of cyclohexane or 0.1 mM NADPH

Xanthobacter sp.

438978

apoenzyme and enzyme complexed with 8-hydroxy-5-deazaflavin is stable on ice for several weeks

Acinetobacter sp.

438972