1.14.13.225: F-actin monooxygenase
This is an abbreviated version!
For detailed information about F-actin monooxygenase, go to the full flat file.
Word Map on EC 1.14.13.225
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1.14.13.225
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plexins
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calponin
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semaphorin-plexin
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sema3a
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plexa
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semaphorin3a
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rab8
- 1.14.13.225
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plexins
- calponin
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semaphorin-plexin
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sema3a
- plexa
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semaphorin3a
- rab8
Reaction
Synonyms
MICAL, MICAL-1, MICAL-2, MICAL1, Mical2, MICAL2PV, MICAL3
ECTree
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Activating Compound
Activating Compound on EC 1.14.13.225 - F-actin monooxygenase
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cofilin
cofilin enhances Mical-mediated actin filament disassembly. Mical and cofilin synergize to drive Semaphorin-Plexin repulsive signalling and axon guidance
actin regulatory protein cofilin strongly suppresses the ability of F-actin to trigger Mical-mediated NADPH consumption
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F-actin
stimulates NADPH oxidation by increasing kcat and kcat/KNADPH about 5 and 200fold, respectively
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the catalytic efficiency of MICAL3 increases on adding F-actin only when the CH domain is available
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additional information
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the catalytic efficiency of MICAL3 increases on adding F-actin only when the CH domain is available
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