1.14.13.225: F-actin monooxygenase
This is an abbreviated version!
For detailed information about F-actin monooxygenase, go to the full flat file.
Word Map on EC 1.14.13.225
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1.14.13.225
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plexins
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calponin
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semaphorin-plexin
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sema3a
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plexa
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semaphorin3a
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rab8
- 1.14.13.225
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plexins
- calponin
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semaphorin-plexin
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sema3a
- plexa
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semaphorin3a
- rab8
Reaction
Synonyms
MICAL, MICAL-1, MICAL-2, MICAL1, Mical2, MICAL2PV, MICAL3
ECTree
1.14.13.225 F-actin monooxygenaseAdvanced search results
results (
results (Engineering
Engineering on EC 1.14.13.225 - F-actin monooxygenase
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
additional information
additional information
expression of truncated forms lacking the C-terminal, LIM and/or calponin homology CH regions. The CH, LIM and C-terminal regions lead to an increase of KmNADPH. The C-terminus also determines an about 10fold decrease of kcat
additional information
construction of enzyme mutants hMCAL3FMOCH, hMICAL3FMO and hMICAL3FMOCHDELTA213,530. The truncated form containing the FMO and CH domains is much more soluble than the full-length form but still retains catalytic activity for F-actin disassembly
additional information
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construction of enzyme mutants hMCAL3FMOCH, hMICAL3FMO and hMICAL3FMOCHDELTA213,530. The truncated form containing the FMO and CH domains is much more soluble than the full-length form but still retains catalytic activity for F-actin disassembly
