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1.14.13.234: 5a,11a-dehydrotetracycline 5-monooxygenase

This is an abbreviated version!
For detailed information about 5a,11a-dehydrotetracycline 5-monooxygenase, go to the full flat file.

Reaction

5a,11a-dehydrotetracycline
+
NADPH
+
H+
+
O2
=
5a,11a-dehydrooxytetracycline
+
NADP+
+
H2O

Synonyms

12-dehydrotetracycline 5-monooxygenase, anhydrotetracycline oxygenase, OtcC, oxyS

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.234 5a,11a-dehydrotetracycline 5-monooxygenase

Organism

Organism on EC 1.14.13.234 - 5a,11a-dehydrotetracycline 5-monooxygenase

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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
bifunctional enzyme, catalyzes the stereospecific hydroxylation of anhydrotetracycline at C-6 (EC 1.14.13.38) and performs an additional hydroxylation at C-5, producing 5a,11a-dehydrooxytetracycline, reaction of EC 1.14.13.234
UniProt
Manually annotated by BRENDA team