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1.14.13.24: 3-hydroxybenzoate 6-monooxygenase

This is an abbreviated version!
For detailed information about 3-hydroxybenzoate 6-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.24

Reaction

3-hydroxybenzoate
+
NADH
 +
H+
 +
O2
=
2,5-Dihydroxybenzoate
 +
NAD+
 +
H2O

Synonyms

3-HBA-6-hydroxylase, 3-hydroxybenzoate 6-hydroxylase, 3-hydroxybenzoate-6-hydroxylase, 3-hydroxybenzoic acid-6-hydroxylase, 3HB6H, m-hydroxybenzoate 6-hydroxylase, MNX2, Mnx2p, NagX, NarX, Ncgl2923, oxygenase, 3-hydroxybenzoate 6-mono-, XlnD

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.24 3-hydroxybenzoate 6-monooxygenase

Reference

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Reference on EC 1.14.13.24 - 3-hydroxybenzoate 6-monooxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
You, K.S.; Arnold, L.J.; Kaplan, N.O.
The stereospecificity of bacterial external flavoprotein monooxygenases for nicotinamide adenine dinucleotide
Arch. Biochem. Biophys.
180
550-554
1977
Pseudomonas aeruginosa, Pseudomonas aeruginosa T1
Manually annotated by BRENDA team
Groseclose, E.E.; Ribbons, D.W.
3-Hydroxybenzoate 6-hydroxylase from Pseudomonas aeruginosa
Biochem. Biophys. Res. Commun.
55
897-903
1973
Pseudomonas aeruginosa, Pseudomonas aeruginosa T1
Manually annotated by BRENDA team
Wang, L.H.; Hamzah, R.Y.; Yu, Y.; Tu, S.C.
Pseudomonas cepacia 3-hydroxybenzoate 6-hydroxylase: induction, purification, and characterization
Biochemistry
26
1099-1104
1987
Burkholderia cepacia
Manually annotated by BRENDA team
Yu, Y.; Wang, L.H.; Tu, S.C.
Pseudomonas cepacia 3-hydroxybenzoate 6-hydroxylase: stereochemistry, isotope effects, and kinetic mechanism
Biochemistry
26
1105-1110
1987
Burkholderia cepacia
Manually annotated by BRENDA team
Rajasekharan, S.; Rajasekharan, R.; Vaidyanathan, C.S.
Substrate-mediated purification and characterization of a 3-hydroxybenzoic acid-6-hydroxylase from Micrococcus
Arch. Biochem. Biophys.
278
21-25
1990
Micrococcus sp.
Manually annotated by BRENDA team
Suarez, M.; Ferrer, E.; Garrido-Pertierra, A.; Martin, M.
Purification and characterization of the 3-hydroxybenzoate-6-hydroxylase from Klebsiella pneumoniae
FEMS Microbiol. Lett.
126
283-290
1995
Klebsiella pneumoniae, Klebsiella pneumoniae M5a1
Manually annotated by BRENDA team
Suemori, A.; Nakajima, K.; Kurane, R.; Nakamura, Y.
Physicochemical and immunochemical characterization of salicylate 5-hydroxylase, m-hydroxybenzoate 6-hydroxylase and p-hydroxybenzoate 3-hydroxylase from Rhodococcus erythropolis
Biotechnol. Lett.
17
1063-1068
1995
Rhodococcus erythropolis, Rhodococcus erythropolis S1
-
Manually annotated by BRENDA team
Sumathi, S.; Dasgupta, D.; Vaidyanathan, C.S.
Chemical modification of 3-HBA-6-hydroxylase by phenylglyoxal: kinetic and physicochemical studies on the modified enzyme
Indian J. Biochem. Biophys.
35
266-272
1998
Micrococcus sp.
Manually annotated by BRENDA team
Sumathi, S.; Dasgupta, D.
Reactivity of 3-HBA-6-hydroxylase with diethylpyrocarbonate and N-bromosuccinimide: Effect of chemical modifications on kinetic and spectral properties of the enzyme
Biotechnol. Prog.
16
577-582
2000
Micrococcus sp.
Manually annotated by BRENDA team
Suresh, S.; Dasgupta, D.
Interaction of 3-hydroxybenzoate with 3-hydroxybenzoate-6-hydroxylase
Biotechnol. Prog.
17
1026-1031
2001
Micrococcus sp.
Manually annotated by BRENDA team
Liu, D.Q.; Liu, H.; Gao, X.L.; Leak, D.J.; Zhou, N.Y.
Arg169 is essential for catalytic activity of 3-hydroxybenzoate 6-hydroxylase from Klebsiella pneumoniae M5a1
Microbiol. Res.
160
53-59
2005
Klebsiella oxytoca (Q5EXK1)
Manually annotated by BRENDA team
Gao, X.; Tan, C.L.; Yeo, C.C.; Poh, C.L.
Molecular and biochemical characterization of the xlnD-encoded 3-hydroxybenzoate 6-hydroxylase involved in the degradation of 2,5-xylenol via the gentisate pathway in Pseudomonas alcaligenes NCIMB 9867
J. Bacteriol.
187
7696-7702
2005
Pseudomonas alcaligenes (Q9F131), Pseudomonas alcaligenes P25X (Q9F131)
Manually annotated by BRENDA team
Park, M.; Jeon, Y.; Jang, H.H.; Ro, H.S.; Park, W.; Madsen, E.L.; Jeon, C.O.
Molecular and biochemical characterization of 3-hydroxybenzoate 6-hydroxylase from Polaromonas naphthalenivorans CJ2
Appl. Environ. Microbiol.
73
5146-5152
2007
Polaromonas naphthalenivorans
Manually annotated by BRENDA team
Liu, T.T.; Xu, Y.; Liu, H.; Luo, S.; Yin, Y.J.; Liu, S.J.; Zhou, N.Y.
Functional characterization of a gene cluster involved in gentisate catabolism in Rhodococcus sp. strain NCIMB 12038
Appl. Microbiol. Biotechnol.
90
671-678
2010
Rhodococcus sp. (E7CYP8), Rhodococcus sp., Rhodococcus sp. NCIMB 12038 (E7CYP8)
Manually annotated by BRENDA team
Yang, Y.F.; Zhang, J.J.; Wang, S.H.; Zhou, N.Y.
Purification and characterization of the ncgl2923-encoded 3-hydroxybenzoate 6-hydroxylase from Corynebacterium glutamicum
J. Basic Microbiol.
50
599-604
2010
Corynebacterium glutamicum (Q8NLB6), Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032 (Q8NLB6), Corynebacterium glutamicum ATCC 13032
Manually annotated by BRENDA team
Sucharitakul, J.; Wongnate, T.; Montersino, S.; van Berkel, W.J.; Chaiyen, P.
Reduction kinetics of 3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1
Biochemistry
51
4309-4321
2012
Rhodococcus jostii
Manually annotated by BRENDA team
Montersino, S.; van Berkel, W.J.
Functional annotation and characterization of 3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1
Biochim. Biophys. Acta
1824
433-442
2012
Rhodococcus jostii
Manually annotated by BRENDA team
Montersino, S.; Orru, R.; Barendregt, A.; Westphal, A.H.; van Duijn, E.; Mattevi, A.; van Berkel, W.J.
Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid-assisted flavoprotein strategy for regioselective aromatic hydroxylation
J. Biol. Chem.
288
26235-26245
2013
Rhodococcus jostii (Q0SFK6)
Manually annotated by BRENDA team
Sucharitakul, J.; Tongsook, C.; Pakotiprapha, D.; van Berkel, W.J.; Chaiyen, P.
The reaction kinetics of 3-hydroxybenzoate 6-hydroxylase from Rhodoccocus jostii RHA1 provide an understanding of the para-hydroxylation enzyme catalytic cycle
J. Biol. Chem.
288
35210-35221
2013
Rhodococcus jostii
Manually annotated by BRENDA team
Holesova, Z.; Jakubkova, M.; Zavadiakova, I.; Zeman, I.; Tomaska, L.; Nosek, J.
Gentisate and 3-oxoadipate pathways in the yeast Candida parapsilosis: identification and functional analysis of the genes coding for 3-hydroxybenzoate 6-hydroxylase and 4-hydroxybenzoate 1-hydroxylase
Microbiology
157
2152-2163
2011
Candida parapsilosis, Candida parapsilosis CDU1
Manually annotated by BRENDA team
Sucharitakul, J.; Medhanavyn, D.; Pakotiprapha, D.; van Berkel, W.J.; Chaiyen, P.
Tyr217 and His213 are important for substrate binding and hydroxylation of 3-hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1
FEBS J.
283
860-881
2016
Rhodococcus jostii (Q0SFK6)
Manually annotated by BRENDA team
Montersino, S.; Te Poele, E.; Orru, R.; Westphal, A.H.; Barendregt, A.; Heck, A.J.R.; van der Geize, R.; Dijkhuizen, L.; Mattevi, A.; van Berkel, W.J.H.
3-Hydroxybenzoate 6-hydroxylase from Rhodococcus jostii RHA1 contains a phosphatidylinositol cofactor
Front. Microbiol.
8
1110
2017
Rhodococcus jostii (Q0SFK6), Rhodococcus jostii
Manually annotated by BRENDA team
Srisook, T.; Vongsetskul, T.; Sucharitakul, J.; Chaiyen, P.; Tangboriboonrat, P.
Immobilization of 3-hydroxybenzoate 6-hydroxylase onto functionalized electrospun polycaprolactone ultrafine fibers A novel heterogeneous catalyst
React. Funct. Polym.
82
41-46
2014
Rhodococcus jostii (Q0SFK6)
-
Manually annotated by BRENDA team
Westphal, A.H.; Tischler, D.; van Berkel, W.J.H.
Natural diversity of FAD-dependent 4-hydroxybenzoate hydroxylases
Arch. Biochem. Biophys.
702
108820
2021
Rhodococcus jostii
Manually annotated by BRENDA team
Chen, X.; Tang, H.; Liu, Y.; Xu, P.; Xue, Y.; Lin, K.; Cui, C.
Purification and initial characterization of 3-hydroxybenzoate 6-hydroxylase from a halophilic Martelella strain AD-3
Front. Microbiol.
9
1335
2018
Martelella sp. AD-3
Manually annotated by BRENDA team