1.14.13.27: 4-aminobenzoate 1-monooxygenase

This is an abbreviated version!
For detailed information about 4-aminobenzoate 1-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.27

Reaction

4-Aminobenzoate
+
NAD(P)H
+ 2 H+ +
O2
=
4-Hydroxyaniline
+
NAD(P)+
+
H2O
+
CO2

Synonyms

4-aminobenzoate hydroxylase, oxygenase, 4-aminobenzoate mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.27 4-aminobenzoate 1-monooxygenase

Substrates Products

Substrates Products on EC 1.14.13.27 - 4-aminobenzoate 1-monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-amino-5-chlorobenzoate + NAD(P)H + O2
4-chloro-2-hydroxyaniline + NAD(P)+ + H2O2 + CO2
show the reaction diagram
-
-
H2O2 formed simultaneously with hydroxylation
?
3,4-diaminobenzoate + NAD(P)H + O2
2-amino-4-hydroxyaniline + NAD(P)+ + H2O2 + CO2
show the reaction diagram
-
17.3% of the reaction with 4-aminobenzoate
H2O2 formed simultaneously with hydroxylation
?
3-chloro-4-aminobenzoate + NAD(P)H + O2
2-chloro-4-hydroxyaniline + NAD(P)H + O2
show the reaction diagram
-
-
-
?
4-amino-2-chlorobenzoate + NAD(P)H + O2
3-chloro-4-hydroxyaniline + NAD(P)+ + H2O2 + CO2
show the reaction diagram
-
-
H2O2 formed simultaneously with hydroxylation
?
4-aminobenzoate + NAD(P)H + O2
4-hydroxyaniline + NAD(P)+ + H2O + CO2
show the reaction diagram
4-aminosalicylate + NAD(P)H + O2
3,4-dihydroxyaniline + NAD(P)+ + H2O2 + CO2
show the reaction diagram
4-hydroxybenzoate + NAD(P)H + O2
quinol + NAD(P)+ + H2O2 + CO2
show the reaction diagram
-
8.4% of the reaction with 4-aminobenzoate
H2O2 formed simultaneously with hydroxylation
?
anthranilate + NAD(P)H + O2
2-hydroxyaniline + NAD(P)+ + H2O2 + CO2
show the reaction diagram
additional information
?
-