1.14.13.29: 4-nitrophenol 2-monooxygenase
This is an abbreviated version!
For detailed information about 4-nitrophenol 2-monooxygenase, go to the full flat file.
Word Map on EC 1.14.13.29
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1.14.13.29
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cyp2e1
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n-demethylase
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ethoxyresorufin
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cyp1a2
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aniline
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pentoxyresorufin
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prod
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o-dealkylase
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diallyl
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n-nitrosodimethylamine
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chlorzoxazone
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aminopyrine
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o-depentylase
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4-methylpyrazole
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cyp2e1-dependent
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benzphetamine
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benzyloxyresorufin
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cyp2e1-mediated
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acetone-induced
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cyp-dependent
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o-deethylation
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2e1-dependent
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7-ethoxyresorufin-o-deethylase
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ethoxycoumarin
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medicine
- 1.14.13.29
- cyp2e1
- n-demethylase
-
ethoxyresorufin
- cyp1a2
- aniline
-
pentoxyresorufin
-
prod
-
o-dealkylase
-
diallyl
- n-nitrosodimethylamine
- chlorzoxazone
- aminopyrine
-
o-depentylase
- 4-methylpyrazole
-
cyp2e1-dependent
- benzphetamine
-
benzyloxyresorufin
-
cyp2e1-mediated
-
acetone-induced
-
cyp-dependent
-
o-deethylation
-
2e1-dependent
- 7-ethoxyresorufin-o-deethylase
-
ethoxycoumarin
- medicine
Reaction
Synonyms
4-nitrophenol 4-monooxygenase/4-nitrocatechol 2-monooxygenase, 4-nitrophenol hydroxylase, 4-nitrophenol-2-hydroxylase, 4-NPH, CYP 2E1, CYP2A/2E1, CYP2E1, cytochrome P-450 2E1, cytochrome P-450 isozyme 3a, NphA1, oxygenase, 4-nitrophenol 2-mono-, p-nitrophenol 2-hydroxylase, p-nitrophenol hydroxylase, p-nitrophenol hydroxylase component A, p-nitrophenol-hydroxylase, PNP 2-monooxygenase, PNP monooxygenase, PnpA1, PNPH, PPH, two-component 4-nitrophenol hydroxylase, two-component PNP monooxygenase
ECTree
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Reference
Reference on EC 1.14.13.29 - 4-nitrophenol 2-monooxygenase
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Mitra, D.; Vaidyanathan, C.S.
A new 4-nitrophenol 2-hydroxylase from a Nocardia sp
Biochem. Int.
8
609-615
1984
Nocardia sp.
Koop, D.R.
Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a
Mol. Pharmacol.
29
399-404
1986
Oryctolagus cuniculus
Arinc, E.; Aydan, A.
Lung microsomal p-nitrophenol hydroxylase - characterization and reconstitution of its activity
Comp. Biochem. Physiol. B
97
455-460
1990
Ovis aries
Reinke, L.A.; Moyer, M.J.
p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol
Drug Metab. Dispos.
13
548-552
1985
Rattus norvegicus
Allis, J.W.; Robinson, B.L.
A kinetic assay for p-nitrophenyl hydroxylase in rat liver microsomes
Anal. Biochem.
219
49-52
1994
Rattus norvegicus
Hanioka, N.; Watanabe, K.; Yoda, R.; Ando, M.
Effect of alachlor on hepatic cytochrome P 450 enzymes in rats
Drug Chem. Toxicol.
25
25-37
2002
Rattus norvegicus
Tassaneeyakul, W.; Veronese, M.E.; Birkett, D.J.; Gonzalez, F.J.; Miners, J.O.
Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
Biochem. Pharmacol.
46
1975-1981
1993
Homo sapiens
Vences-Mejia, A.; Labra-Ruiz, N.; Hernandez-Martinez, N.; Dorado-Gonzalez, V.; Gomez-Garduno, J.; Perez-Lopez, I.; Nosti-Palacios, R.; Camacho Carranza, R.; Espinosa-Aguirre, J.J.
The effect of aspartame on rat brain xenobiotic-metabolizing enzymes
Hum. Exp. Toxicol.
25
453-459
2006
Rattus norvegicus
Pakala, S.B.; Gorla, P.; Pinjari, A.B.; Krovidi, R.K.; Baru, R.; Yanamandra, M.; Merrick, M.; Siddavattam, D.
Biodegradation of methyl parathion and p-nitrophenol: Evidence for the presence of a p-nitrophenol 2-hydroxylase in a Gram-negative Serratia sp. strain DS001
Appl. Microbiol. Biotechnol.
73
1452-1462
2007
Serratia sp. DS001
Zamaratskaia, G.; Zlabek, V.; Chen, G.; Madej, A.
Modulation of porcine cytochrome P450 enzyme activities by surgical castration and immunocastration
Animal
3
1124-1132
2009
Sus scrofa
Carvalho, R.S.; Friedrich, K.; De-Oliveira, A.C.; Suarez-Kurtz, G.; Paumgartten, F.J.
Malaria downmodulates mRNA expression and catalytic activities of CYP1A2, 2E1 and 3A11 in mouse liver
Eur. J. Pharmacol.
616
265-269
2009
Mus musculus
Takeo, M.; Murakami, M.; Niihara, S.; Yamamoto, K.; Nishimura, M.; Kato, D.; Negoro, S.
Mechanism of 4-nitrophenol oxidation in Rhodococcus sp. Strain PN1: characterization of the two-component 4-nitrophenol hydroxylase and regulation of its expression
J. Bacteriol.
190
7367-7374
2008
Rhodococcus sp. PN1 (Q8RQQ0)
Wagner, L.; Zlabek, V.; Trattner, S.; Zamaratskaia, G.
In vitro inhibition of 7-ethoxyresorufin-O-deethylase (EROD) and p-nitrophenol hydroxylase (PNPH) activities by sesamin in hepatic microsomes from two fish species
Mol. Biol. Rep.
40
457-462
2013
Cyprinus carpio, Salmo salar
Min, J.; Zhang, J.J.; Zhou, N.Y.
The gene cluster for para-nitrophenol catabolism is responsible for 2-chloro-4-nitrophenol degradation in Burkholderia sp. strain SJ98
Appl. Environ. Microbiol.
80
6212-6222
2014
Rhodococcus opacus, Rhodococcus opacus RKJ300
Kallubai, M.; Amineni, U.; Mallavarapu, M.; Kadiyala, V.
In silico approach to support that p-nitrophenol monooxygenase from Arthrobacter sp. strain JS443 catalyzes the initial two sequential monooxygenations
Interdiscip. Sci.
7
157-167
2015
Arthrobacter sp. JS443
Kallubai, M.; Amineni, U.; Mallavarapu, M.; Kadiyala, V.
In silico approach to support that p-nitrophenol monooxygenase from Arthrobacter sp. strain JS443 catalyzes the initial two sequential monooxygenations
Interdiscip. Sci. Comput. Life Sci.
7
157-167
2015
Lysinibacillus sphaericus, Arthrobacter sp. (A7YVV2), Arthrobacter sp., Lysinibacillus sphaericus JS905
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