1.14.13.35: anthranilate 3-monooxygenase (deaminating)
This is an abbreviated version!
For detailed information about anthranilate 3-monooxygenase (deaminating), go to the full flat file.
Word Map on EC 1.14.13.35
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1.14.13.35
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flavoproteins
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flavin
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niger
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trichosporon
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catechols
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salicylate
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2,3-dihydroxybenzoate
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deaminate
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cutaneum
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hydroxylases
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imine
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nonhydroxylated
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fmn
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p-hydroxybenzoate
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half-reaction
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massey
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flavodoxin
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l-kynurenine
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ballou
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flavoenzyme
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d-amino
- 1.14.13.35
- flavoproteins
- flavin
- niger
-
trichosporon
- catechols
- salicylate
- 2,3-dihydroxybenzoate
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deaminate
- cutaneum
- hydroxylases
- imine
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nonhydroxylated
- fmn
- p-hydroxybenzoate
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half-reaction
-
massey
- flavodoxin
- l-kynurenine
-
ballou
-
flavoenzyme
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d-amino
Reaction
Synonyms
anthranilate 2,3-dioxygenase (deaminating), anthranilate 2,3-hydroxylase (deaminating), anthranilate hydroxylase, anthranilate hydroxylase (deaminating), anthranilic hydroxylase, EC 1.14.12.2
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Reaction
Reaction on EC 1.14.13.35 - anthranilate 3-monooxygenase (deaminating)
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mechanism
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anthranilate + NADPH + H+ + O2 = 2,3-dihydroxybenzoate + NADP+ + NH3
mechanism proposed involving imine formation and hydrolysis during the reaction with the flavin peroxide formed from reduced enzyme flavin and molecular oxygen
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anthranilate + NADPH + H+ + O2 = 2,3-dihydroxybenzoate + NADP+ + NH3
possible involvement of superoxide anion (O2-) in the reaction
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