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1.14.13.4: melilotate 3-monooxygenase

This is an abbreviated version!
For detailed information about melilotate 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.4

Reaction

3-(2-hydroxyphenyl)propanoate
+
NADH
+
H+
+
O2
=
3-(2,3-dihydroxyphenyl)propanoate
+
NAD+
+
H2O

Synonyms

2-hydroxyphenylpropionate hydroxylase, 2-hydroxyphenylpropionic hydroxylase, melilotate hydroxylase, melilotic hydroxylase, oxygenase, melilotate 3-mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.4 melilotate 3-monooxygenase

Reference

Reference on EC 1.14.13.4 - melilotate 3-monooxygenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Flashner, M.S.; Massey, V.
Flavoprotein oxygenases
Mol. Mech. Oxygen Activ. (Hayaishi, O., ed.) Academic Press, New York
245-283
1974
Arthrobacter sp., Pseudomonas sp.
-
Manually annotated by BRENDA team
Levy, C.C.
Melilotate hydroxylase. Purification of the enzyme and the nature of the prosthetic group
J. Biol. Chem.
242
747-753
1967
Arthrobacter sp.
Manually annotated by BRENDA team
Strickland, S.; Massey, V.
The purification and properties of the flavoprotein melilotate hydroxylase
J. Biol. Chem.
248
2944-2952
1973
Pseudomonas sp.
Manually annotated by BRENDA team
Levy, C.C.; Frost, P.
The metabolism of coumarin by a microorganism. V. Melilotate hydroxylase
J. Biol. Chem.
241
997-1003
1966
Arthrobacter sp.
Manually annotated by BRENDA team
Strickland, S.; Massey, V.
The mechanism of action of the flavoprotein melilotate hydroxylase
J. Biol. Chem.
248
2953-2962
1973
Pseudomonas sp.
Manually annotated by BRENDA team
Strickland, S.; Schopfer, L.M.; Massey, V.
Kinetic and mechanistic studies on the reaction of melilotate hydroxylase with deuterated melilotate
Biochemistry
14
2230-2235
1975
Pseudomonas sp.
Manually annotated by BRENDA team
Schopfer, L.M.; Massey, V.
Kinetic and mechanistic studies on the reduction of melilotate hydroxylase by reduced pyridine nucleotides
J. Biol. Chem.
254
10634-10643
1979
Pseudomonas sp.
Manually annotated by BRENDA team
Manstein, D.J.; Pai, E.F.
Absolute stereochemistry of flavins in enzyme-catalyzed reactions
Biochemistry
25
6807-6816
1986
Pseudomonas sp.
Manually annotated by BRENDA team
You, K.S.; Arnold, L.J.; Kaplan, N.O.
The stereospecificity of bacterial external flavoprotein monooxygenases for nicotinamide adenine dinucleotide
Arch. Biochem. Biophys.
180
550-554
1977
Pseudomonas sp.
Manually annotated by BRENDA team