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1.14.13.64: 4-hydroxybenzoate 1-hydroxylase

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate 1-hydroxylase, go to the full flat file.

Word Map on EC 1.14.13.64

Reaction

4-hydroxybenzoate
+
NAD(P)H
 +
H+
 +
O2
=
hydroquinone
 +
NAD(P)+
 +
H2O
 +
CO2

Synonyms

4-hydroxybenzoate 1-hydroxylase, 4-hydroxybenzoate 1-hydroxylase (decarboxylating), 4-hydroxybenzoate 1-monooxygenase, 4HB1H, Cp_4HB1H, FAD-dependent 4-hydroxybenzoate hydroxylase, MNX1, Mnx1p, Oxygenase, 4-hydroxybenzoate 1-mono, PHBH, V1H, vanillate 1-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.64 4-hydroxybenzoate 1-hydroxylase

Cloned

Cloned on EC 1.14.13.64 - 4-hydroxybenzoate 1-hydroxylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
a 4-hydroxybenzoate 1-hydroxylase gene from Candida parapsilosis CBS604 and a glucosyltransferase (arbutin synthase) gene from Rauvolfia serpentina are introduced into Escherichia coli lead to the production of 54.71 mg/l of arbutin from glucose
gene mnx1, sequence comparisons and phylogenetic analysis and tree, recombinant expression of C-terminally His-tagged enzyme in Escherichia coli strain TOP10
-
yes, gene mnx1, quantitative real-time PCR enzyme expression analysis, recombinant overexpression in Yarrowia lipolytica strain polf, coexpression with chorismate pyruvate-lyase (UbiC) and hydroquinone glucosyltransferase (AS)
-