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1.14.13.69: alkene monooxygenase

This is an abbreviated version!
For detailed information about alkene monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.69

Reaction

Propene
+
NADH
 +
H+
 +
O2
=
1,2-Epoxypropane
 +
NAD+
 +
H2O

Synonyms

AkMO, alkene epoxygenase, alkene monooxygenase, AMO, ethene MO, EtnABCD, EtnC, etnD, IsoMO, isoprene monooxygenase, More, PmoABCD, propene MO, propene monooxygenase, XAMO

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.69 alkene monooxygenase

Activating Compound

Activating Compound on EC 1.14.13.69 - alkene monooxygenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
AamD
the enzyme requires interaction with the small catalytic coupling/effector protein, substitution of AamD with IsoD, the coupling protein from the closely related isoprene monooxygenase, changes the regioselectivity of toluene hydroxylation and stereoselectivity of styrene epoxidation, although this is accompanied by a high level of uncoupling
-
additional information
-
epoxyethane, a metabolic intermediate of ethene biodegradation, induces enzyme expression, acetate reactivates extant AkMO in starved vinyl chloride- or ethene-grown cultures, overview
-