1.14.13.9: kynurenine 3-monooxygenase

This is an abbreviated version!
For detailed information about kynurenine 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.9

Reaction

L-kynurenine
+
NADPH
+
H+
+
O2
=
3-hydroxy-L-kynurenine
+
NADP+
+
H2O

Synonyms

Bna4, cinnabar, EC 1.14.1.2, EC 1.99.1.5, K3H, KMO, KYN-OHase, kynurenine 3-hydroxylase, kynurenine hydroxylase, kynurenine monooxygenase, L-kynurenine 3-monooxygenase, L-kynurenine,NADPH2:oxygen oxidoreductase (3-hydroxylating), L-kynurenine-3-hydroxylase, More, oxygenase, kynurenine 3-mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.9 kynurenine 3-monooxygenase

Molecular Weight

Molecular Weight on EC 1.14.13.9 - kynurenine 3-monooxygenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
160000
-
2 * 160000 in 0.2% Triton-X100, SDS-PAGE
200000
-
or more, gel filtration, SDS-PAGE
345000
-
gel filtration
49000
-
SDS-PAGE
50000
-
x * 50000, recombinant enzyme, SDS-PAGE
54000
x * 54000, recombinant soluble enzyme not counting the His-tag, SDS-PAGE
55000
-
SDS-PAGE
55760
60000
x * 60000, recombinant enzyme, SDS-PAGE
60386
calculated from sequence
62136
native mass spectrum analysis