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1.14.13.B34: N-demethylase reductase

This is an abbreviated version!
For detailed information about N-demethylase reductase, go to the full flat file.

Reaction

Synonyms

NdmD, Rieske nonheme iron oxygenase reductase, RO reductase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                EC 1.14.13.B341.14.13.B34 N-demethylase reductase

Engineering

Engineering on EC 1.14.13.B34 - N-demethylase reductase

for references in articles please use BRENDA:EC1.14.13.B34

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
to determine the role of N-terminal Rieske domain in NdmD reductase activity, two deletion constructs DELTA114NdmD and DELTA250NdmD are made. Cytochrome c reductase (ccr) activity of the NdmD constructs and demethylase activity of NdmA in the presence of NdmD constructs show that there is no significant difference in the catalytic activity of NdmD upon deletion of its N-terminal Rieske domain