1.14.14.12: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase

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For detailed information about 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase, go to the full flat file.

Reaction

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

Synonyms

3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase, HsaAB

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.12 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase

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Results	in table
811	AA Sequence
1	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
2	General Information
1	Inhibitors
5	kcat/KM [mM/s]
5	KM Value [mM]
2	Natural Substrates/ Products (Substrates)
2	Organism
6	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
2	Reference
11	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Turnover Number [1/s]

Reaction

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Reaction on EC 1.14.14.12 - 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase

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3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O