1.14.14.145: abieta-7,13-dien-18-ol hydroxylase
This is an abbreviated version!
For detailed information about abieta-7,13-dien-18-ol hydroxylase, go to the full flat file.
Word Map on EC 1.14.14.145
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1.14.14.145
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cyp1a1
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diterpene
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pinus
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taeda
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loblolly
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picea
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conifer
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nadph-cytochrome
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olefins
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levopimaradiene
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spruce
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abietadiene
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abietic
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oleoresin
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sitchensis
- 1.14.14.145
- cyp1a1
-
diterpene
-
pinus
- taeda
-
loblolly
-
picea
-
conifer
-
nadph-cytochrome
-
olefins
- levopimaradiene
- spruce
- abietadiene
-
abietic
-
oleoresin
- sitchensis
Reaction
Synonyms
abieta-7,13-dien-18-ol hydroxylase, abietadienol/abietadienal oxidase, CYP720B1, CyPA, CYPA1, CYPA2, CyPB, CYPC, CYPD, EC 1.14.13.109, PtAO
ECTree
1.14.14.145 abieta-7,13-dien-18-ol hydroxylaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.14.14.145 - abieta-7,13-dien-18-ol hydroxylase
for references in articles please use BRENDA:EC1.14.14.145
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY 
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(13S)-pimara-7,15-dien-18-al + [reduced NADPH-hemoprotein reductase] + O2
(13S)-pimara-7,15-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: -
Products: -
Products: -
?
abieta-7,13-dien-18-al + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: -
Products: -
Products: -
?
abieta-7,13-dien-18-ol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2
abieta-7,13-dien-18-oate + 2 [oxidized NADPH-hemoprotein reductase] + 3 H2O
Substrates: -
Products: -
Products: -
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
abietadienal + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: oxidation at C-18
Products: -
Products: -
?
abietadienol + [reduced NADPH-hemoprotein reductase] + O2
abietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: oxidation at C-18
Products: -
Products: -
?
dehydroabietadienal + [reduced NADPH-hemoprotein reductase] + O2
dehydroabietadienoate + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: oxidation at C-18
Products: -
Products: -
?
dehydroabietadienol + [reduced NADPH-hemoprotein reductase] + O2
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
isopimara-7,15-dienal + [reduced NADPH-hemoprotein reductase] + O2
isopimara-7,15-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: oxidation at C-18
Products: -
Products: -
?
isopimara-7,15-dienol + [reduced NADPH-hemoprotein reductase] + O2
isopimara-7,15-dienal + [oxidized NADPH-hemoprotein reductase] + H2O
levopimaradienol + [reduced NADPH-hemoprotein reductase] + O2
levopimaradienal + [oxidized NADPH-hemoprotein reductase] + H2O
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
-
Substrates: -
Products: -
Products: -
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
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Substrates: activity is induced by wounding of the plant tissue reaching a maximum at 10 days after wounding with about a 60fold increase for the abietadienol hydroxylase
Products: -
Products: -
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
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Substrates: this enzyme catalyzes a step in the pathway of abietic acid biosynthesis. Hydroxylation activity is maximally supported by NADPH, and NADH is less effective as reductant
Products: -
Products: -
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
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Substrates: this enzyme catalyzes a step in the pathway of abietic acid biosynthesis
Products: -
Products: -
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: -
Products: -
Products: -
?
abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2
abieta-7,13-dien-18-al + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: PtAO catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine diterpene resin acid biosynthesis
Products: -
Products: -
?
dehydroabietadienol + [reduced NADPH-hemoprotein reductase] + O2
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: -
Products: -
Products: -
?
dehydroabietadienol + [reduced NADPH-hemoprotein reductase] + O2
dehydroabietadienal + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: oxidation at C-18
Products: -
Products: -
?
isopimara-7,15-dienol + [reduced NADPH-hemoprotein reductase] + O2
isopimara-7,15-dienal + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: -
Products: -
Products: -
?
isopimara-7,15-dienol + [reduced NADPH-hemoprotein reductase] + O2
isopimara-7,15-dienal + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: oxidation at C-18
Products: -
Products: -
?
levopimaradienol + [reduced NADPH-hemoprotein reductase] + O2
levopimaradienal + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: -
Products: -
Products: -
?
levopimaradienol + [reduced NADPH-hemoprotein reductase] + O2
levopimaradienal + [oxidized NADPH-hemoprotein reductase] + H2O
Substrates: oxidation at C-18
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
Products: -
Products: -
?
additional information
?
-
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense
Products: -
Products: -
?
additional information
?
-
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme is involved in formation of diterpene resin acids, DRAs, in pine, and plays an important role in constitutive and induced oleoresin defense, the enzyme catalyzes an array of consecutive oxidation steps with several different diterpenol and diterpenal intermediates in loblolly pine DRA biosynthesis
Products: -
Products: -
?
additional information
?
-
-
Substrates: the enzyme CYP720B1 is a multifunctional, multisubstrate cytochrome P450 monooxygenase
Products: -
Products: -
?
additional information
?
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Substrates: the enzyme CYP720B1 is a multifunctional, multisubstrate cytochrome P450 monooxygenase
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme CYP720B1 is a multifunctional, multisubstrate cytochrome P450 monooxygenase
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme CYP720B1 is a multifunctional, multisubstrate cytochrome P450 monooxygenase
Products: -
Products: -
?
additional information
?
-
Substrates: the enzyme CYP720B1 is a multifunctional, multisubstrate cytochrome P450 monooxygenase
Products: -
Products: -
?
additional information
?
-
-
Substrates: the recombinant enzyme catalyzed the oxidation of multiple diterpene alcohol and aldehydes. It is not able to oxidize abietadiene. No activity with neoabietadienol or neoabietadienal
Products: -
Products: -
?
additional information
?
-
Substrates: the recombinant enzyme catalyzed the oxidation of multiple diterpene alcohol and aldehydes. It is not able to oxidize abietadiene. No activity with neoabietadienol or neoabietadienal
Products: -
Products: -
?
additional information
?
-
Substrates: the recombinant enzyme catalyzed the oxidation of multiple diterpene alcohol and aldehydes. It is not able to oxidize abietadiene. No activity with neoabietadienol or neoabietadienal
Products: -
Products: -
?
additional information
?
-
Substrates: the recombinant enzyme catalyzed the oxidation of multiple diterpene alcohol and aldehydes. It is not able to oxidize abietadiene. No activity with neoabietadienol or neoabietadienal
Products: -
Products: -
?
additional information
?
-
Substrates: the recombinant enzyme catalyzed the oxidation of multiple diterpene alcohol and aldehydes. It is not able to oxidize abietadiene. No activity with neoabietadienol or neoabietadienal
Products: -
Products: -
?
