1.14.14.30: isobutylamine N-monooxygenase
This is an abbreviated version!
For detailed information about isobutylamine N-monooxygenase, go to the full flat file.
Reaction
Synonyms
IBAH, isobutylamine N-hydroxylase, vlmH
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.14.14.30 - isobutylamine N-monooxygenase
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REACTION DIAGRAM
N-hydroxy-2-methylpropan-1-amine + FAD + H2O
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2-methylpropanamine + FADH2 + O2
N-hydroxy-2-methylpropan-1-amine + FAD + H2O
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?
N-hydroxy-2-methylpropan-1-amine + FMN + H2O
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2-methylpropanamine + FMNH2 + O2
N-hydroxy-2-methylpropan-1-amine + FMN + H2O
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?
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amine N-hydroxylase cannot carry out the reduction of the flavin cofactor. Rather, the reduced flavin is supplied by a separate flavin reductase. The mechanism for the hydroxylation is likely to proceed via the formation of a flavin 4a-hydroperoxide
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additional information
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amine N-hydroxylase cannot carry out the reduction of the flavin cofactor. Rather, the reduced flavin is supplied by a separate flavin reductase. The mechanism for the hydroxylation is likely to proceed via the formation of a flavin 4a-hydroperoxide
-
-
?