1.14.14.33: ethylenediaminetetraacetate monooxygenase

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For detailed information about ethylenediaminetetraacetate monooxygenase, go to the full flat file.

Reaction

Synonyms

EmoA

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.33 ethylenediaminetetraacetate monooxygenase

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Results	in table
2	Activating Compound
5	AA Sequence
4	Application
2	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
3	Expression
9	General Information
8	kcat/KM [mM/s]
10	KM Value [mM]
2	Metals/Ions
1	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
13	Organism
1	pH Optimum
2	pH Range
7	Protein Variants
1	Purification (Commentary)
3	Reaction
11	Reference
12	Specific Activity [micromol/min/mg]
26	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Temperature Range [°C]
10	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.14.14.33 - ethylenediaminetetraacetate monooxygenase

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SYSTEMATIC NAME

IUBMB Comments

ethylenediaminetetraacetate,FMNH2:O2 oxidoreductase (glyoxylate-forming)

The enzyme is part of a two component system that also includes EC 1.5.1.42, FMN reductase (NADH), which provides reduced flavin mononucleotide for this enzyme. It acts on EDTA only when it is complexed with divalent cations such as Mg2+, Zn2+, Mn2+, Co2+, or Cu2+. While the enzyme has a substrate overlap with EC 1.14.14.10, nitrilotriacetate monooxygenase, it has a much wider substrate range, which includes nitrilotriacetate (NTA) and diethylenetriaminepentaacetate (DTPA) in addition to EDTA.