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1.14.14.47: nitric-oxide synthase (flavodoxin)

This is an abbreviated version!
For detailed information about nitric-oxide synthase (flavodoxin), go to the full flat file.

Word Map on EC 1.14.14.47

Reaction

2 L-arginine + 2 reduced flavodoxin + 2 O2 = 2 Nomega-hydroxy-L-arginine + 2 oxidized flavodoxin + 2 H2O

Synonyms

bNOS, GK1676, nitric oxide synthetase, NO synthase, NOS, SANOS, YumC

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.47 nitric-oxide synthase (flavodoxin)

Activating Compound

Activating Compound on EC 1.14.14.47 - nitric-oxide synthase (flavodoxin)

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
tryptophan
-
stimulates oxidation of substrate L-arginine. Tryptophan or a derivative thereof may bind in the enzyme's pterin site, participate in arginine oxidation, and become nitrated at the 4-position