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1.14.14.48: jasmonoyl-L-amino acid 12-hydroxylase

This is an abbreviated version!
For detailed information about jasmonoyl-L-amino acid 12-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.48

Reaction

a jasmonoyl-L-amino acid
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
a 12-hydroxyjasmonoyl-L-amino acid
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

CYP94B1, CYP94B3, JA-Ile 12-hydroxylase, JA-Ile-12-hydroxylase, jasmonoyl-L-isoleucine-12-hydroxylase, jasmonyl-L-isoleucine 12-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.48 jasmonoyl-L-amino acid 12-hydroxylase

Reference

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Reference on EC 1.14.14.48 - jasmonoyl-L-amino acid 12-hydroxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Poudel, A.N.; Zhang, T.; Kwasniewski, M.; Nakabayashi, R.; Saito, K.; Koo, A.J.
Mutations in jasmonoyl-L-isoleucine-12-hydroxylases suppress multiple JA-dependent wound responses in Arabidopsis thaliana
Biochim. Biophys. Acta
1861
1396-1408
2016
Arabidopsis thaliana (Q9FMV7), Arabidopsis thaliana (Q9SMP5), Arabidopsis thaliana
Manually annotated by BRENDA team
Luo, J.; Wei, K.; Wang, S.; Zhao, W.; Ma, C.; Hettenhausen, C.; Wu, J.; Cao, G.; Sun, G.; Baldwin, I.T.; Wu, J.; Wang, L.
COI1-regulated hydroxylation of jasmonoyl-L-isoleucine impairs Nicotiana attenuata's resistance to the generalist herbivore Spodoptera litura
J. Agric. Food Chem.
64
2822-2831
2016
Nicotiana attenuata (A0A1J6JQE7), Nicotiana attenuata
Manually annotated by BRENDA team
Heitz, T.; Widemann, E.; Lugan, R.; Miesch, L.; Ullmann, P.; Desaubry, L.; Holder, E.; Grausem, B.; Kandel, S.; Miesch, M.; Werck-Reichhart, D.; Pinot, F.
Cytochromes P450 CYP94C1 and CYP94B3 catalyze two successive oxidation steps of plant hormone jasmonoyl-isoleucine for catabolic turnover
J. Biol. Chem.
287
6296-6306
2012
Arabidopsis thaliana (Q9SMP5)
Manually annotated by BRENDA team
Koo, A.J.; Thireault, C.; Zemelis, S.; Poudel, A.N.; Zhang, T.; Kitaoka, N.; Brandizzi, F.; Matsuura, H.; Howe, G.A.
Endoplasmic reticulum-associated inactivation of the hormone jasmonoyl-L-isoleucine by multiple members of the cytochrome P450 94 family in Arabidopsis
J. Biol. Chem.
289
29728-29738
2014
Arabidopsis thaliana (Q9FMV7), Arabidopsis thaliana (Q9SMP5)
Manually annotated by BRENDA team
Aubert, Y.; Widemann, E.; Miesch, L.; Pinot, F.; Heitz, T.
CYP94-mediated jasmonoyl-isoleucine hormone oxidation shapes jasmonate profiles and attenuates defence responses to Botrytis cinerea infection
J. Exp. Bot.
66
3879-3892
2015
Arabidopsis thaliana (Q9SMP5)
Manually annotated by BRENDA team
Widemann, E.; Grausem, B.; Renault, H.; Pineau, E.; Heinrich, C.; Lugan, R.; Ullmann, P.; Miesch, L.; Aubert, Y.; Miesch, M.; Heitz, T.; Pinot, F.
Sequential oxidation of jasmonoyl-phenylalanine and jasmonoyl-isoleucine by multiple cytochrome P450 of the CYP94 family through newly identified aldehyde intermediates
Phytochemistry
117
388-399
2015
Arabidopsis thaliana (Q9SMP5)
Manually annotated by BRENDA team
Kitaoka, N.; Kawaide, H.; Amano, N.; Matsubara, T.; Nabeta, K.; Takahashi, K.; Matsuura, H.
CYP94B3 activity against jasmonic acid amino acid conjugates and the elucidation of 12-O-beta-glucopyranosyl-jasmonoyl-L-isoleucine as an additional metabolite
Phytochemistry
99
6-13
2014
Arabidopsis thaliana (Q9SMP5)
Manually annotated by BRENDA team
Kitaoka, N.; Matsubara, T.; Sato, M.; Takahashi, K.; Wakuta, S.; Kawaide, H.; Matsui, H.; Nabeta, K.; Matsuura, H.
Arabidopsis CYP94B3 encodes jasmonyl-L-isoleucine 12-hydroxylase, a key enzyme in the oxidative catabolism of jasmonate
Plant Cell Physiol.
52
1757-1765
2011
Arabidopsis thaliana (Q9SMP5)
Manually annotated by BRENDA team
Bruckhoff, V.; Haroth, S.; Feussner, K.; Koenig, S.; Brodhun, F.; Feussner, I.
Functional characterization of CYP94-genes and identification of a novel jasmonate catabolite in flowers
PLoS ONE
11
e0159875
2016
Arabidopsis thaliana (Q9FMV7), Arabidopsis thaliana (Q9SMP5), Arabidopsis thaliana
Manually annotated by BRENDA team
Koo, A.J.; Cooke, T.F.; Howe, G.A.
Cytochrome P450 CYP94B3 mediates catabolism and inactivation of the plant hormone jasmonoyl-L-isoleucine
Proc. Natl. Acad. Sci. USA
108
9298-9303
2011
Arabidopsis thaliana (Q9SMP5)
Manually annotated by BRENDA team