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1.14.14.48: jasmonoyl-L-amino acid 12-hydroxylase

This is an abbreviated version!
For detailed information about jasmonoyl-L-amino acid 12-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.48

Reaction

a jasmonoyl-L-amino acid
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
a 12-hydroxyjasmonoyl-L-amino acid
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP94B1, CYP94B3, JA-Ile 12-hydroxylase, JA-Ile-12-hydroxylase, jasmonoyl-L-isoleucine-12-hydroxylase, jasmonyl-L-isoleucine 12-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.48 jasmonoyl-L-amino acid 12-hydroxylase

Systematic Name

Systematic Name on EC 1.14.14.48 - jasmonoyl-L-amino acid 12-hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
jasmonoyl-L-amino acid,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
A cytochrome P450 (heme thiolate) enzyme found in plants. The enzyme acts on jasmonoyl-L-amino acid conjugates, catalysing the hydroxylation of the C-12 position of jasmonic acid. While the best studied substrate is (+)-7-epi-jasmonoyl-L-isoleucine, the enzyme was shown to be active with jasmonoyl-L-valine and jasmonoyl-L-phenylalanine, and is likely to be active with other jasmonoyl-amino acid conjugates.