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1.14.14.B10: heme oxygenase (hematinic acid-producing)

This is an abbreviated version!
For detailed information about heme oxygenase (hematinic acid-producing), go to the full flat file.

Reaction

heme
+
H2O2
=
hematinic acid
+
a tripyrrole
+
Fe3+

Synonyms

ChuS

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.B10 heme oxygenase (hematinic acid-producing)

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Resultsin table
1AA Sequence
1Cofactor
2Expression
2General Information
1Natural Substrates/ Products (Substrates)
3Organism
1Reaction
3Reference
2Substrates and Products (Substrate)
3Synonyms
1Systematic Name

Reference

Reference on EC 1.14.14.B10 - heme oxygenase (hematinic acid-producing)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ouellet, Y.H.; Ndiaye, C.T.; Gagne, S.M.; Sebilo, A.; Suits, M.D.; Jubinville, E.; Jia, Z.; Ivancich, A.; Couture, M.
An alternative reaction for heme degradation catalyzed by the Escherichia coli O157 H7 ChuS protein Release of hematinic acid, tripyrrole and Fe(III)
J. Inorg. Biochem.
154
103-113
2016
Escherichia coli (Q8X5N8)
Manually annotated by BRENDA team
Maharshak, N.; Ryu, H.S.; Fan, T.J.; Onyiah, J.C.; Schulz, S.; Otterbein, S.L.; Wong, R.; Hansen, J.J.; Otterbein, L.E.; Carroll, I.M.; Plevy, S.E.
Escherichia coli heme oxygenase modulates host innate immune responses
Microbiol. Immunol.
59
452-465
2015
Escherichia coli, Escherichia coli NC101
Manually annotated by BRENDA team