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1.14.14.B11: nicotine demethylase

This is an abbreviated version!
For detailed information about nicotine demethylase, go to the full flat file.

Word Map on EC 1.14.14.B11

Reaction

(R)-nicotine
+
O2
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(R)-nornicotine
+
formaldehyde
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP82E, CYP82E1, CYP82E10, CYP82E2, CYP82E21, CYP82E3, CYP82E4, CYP82E4v1, CYP82E5v2, nicotine N-demethylase, NND

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.B11 nicotine demethylase

Disease

Disease on EC 1.14.14.B11 - nicotine demethylase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Virus Diseases
CYP82E4-mediated nicotine to nornicotine conversion in tobacco is regulated by a senescence-specific signaling pathway.