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1.14.14.B9: fatty acid omega2/3-hydroxyase

This is an abbreviated version!
For detailed information about fatty acid omega2/3-hydroxyase, go to the full flat file.

Reaction

(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosa-4,7,10,13,16-pentaenoate
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP4F11, CYP4F12, CYP4F8

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.B9 fatty acid omega2/3-hydroxyase

Reference

Reference on EC 1.14.14.B9 - fatty acid omega2/3-hydroxyase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stark, K.; Wongsud, B.; Burman, R.; Oliw, E.H.
Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8
Arch. Biochem. Biophys.
441
174-181
2005
Homo sapiens (P98187), Homo sapiens (Q9HCS2)
Manually annotated by BRENDA team
Uehara, S.; Murayama, N.; Nakanishi, Y.; Nakamura, C.; Hashizume, T.; Zeldin, D.C.; Yamazaki, H.; Uno, Y.
Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine
Xenobiotica
45
124-130
2015
Macaca fascicularis (A8CBR8), Macaca fascicularis (A8CBS0)
Manually annotated by BRENDA team