1.2.1.100: 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase

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For detailed information about 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, go to the full flat file.

Reaction

5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate

3-hydroxy-2-methylpyridine-4,5-dicarboxylate

Synonyms

mlr6739, mlr6793

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.100 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase

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Results	in table
2	AA Sequence
1	Cloned(Commentary)
1	Crystallization (Commentary)
1	Expression
2	General Information
6	KM Value [mM]
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
5	Organism
3	Pathway
3	pH Optimum
4	Protein Variants
1	Reaction
4	Reference
8	Substrates and Products (Substrate)
3	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Turnover Number [1/s]

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Reference on EC 1.2.1.100 - 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase

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744227

Mugo, A.N.; Kobayashi, J.; Mikami, B.; Yoshikane, Y.; Yagi, T.; Ohnishi, K.

Crystal structure of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase from Mesorhizobium loti

Biochem. Biophys. Res. Commun.

456

35-40

2015

Mesorhizobium japonicum (Q988C8)

25446130

745236

Yokochi, N.; Yoshikane, Y.; Matsumoto, S.; Fujisawa, M.; Ohnishi, K.; Yagi, T.

Gene identification and characterization of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase

J. Biochem.

145

493-503

2009

Mesorhizobium loti (Q988H5), Mesorhizobium loti, Mesorhizobium loti MAFF303099 (Q988H5)

19218190

745254

Lee, Y.; Nelson, M.; Snell, E.

Enzymes of vitamin B6 degradation. Purification and properties of isopyridoxal dehydrogenase and 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylic-acid dehydrogenase

J. Biol. Chem.

261

15106-15111

1986

Pseudomonas sp. MA-1

3533936