1.2.1.18: malonate-semialdehyde dehydrogenase (acetylating)

This is an abbreviated version!
For detailed information about malonate-semialdehyde dehydrogenase (acetylating), go to the full flat file.

Reaction

Synonyms

Aldh6a1, dehydrogenase, malonate semialdehyde, FG99_15390, KES23460, malonate semialdehyde oxidative decarboxylase, malonate-semialdehyde dehydrogenase, malonate-semialdehyde dehydrogenase (NADP+) (acylating), malonate-semialdehyde: nicotinamide adenine dinucleotide oxidoreductase, malonic semialdehyde oxidative decarboxylase, methylmalonate-semialdehyde dehydrogenase, NAD-dependent malonate-semialdehyde dehydrogenase

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
1427	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
14	Cofactor
1	Crystallization (Commentary)
35	Disease/ Diagnostics
2	General Stability
4	Inhibitors
7	KM Value [mM]
4	Localization
2	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
13	Organism
11	Pathway
7	pH Optimum
2	pH Range
5	Purification (Commentary)
1	Reaction
3	Reaction Type
11	Reference
18	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
17	Substrates and Products (Substrate)
3	Subunits
17	Synonyms
1	Systematic Name

Disease

topprint

print visible entries

print all entries

Disease on EC 1.2.1.18 - malonate-semialdehyde dehydrogenase (acetylating)

Please use the Disease Search for a specific query.

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Atherosclerosis

Common dysregulated pathways in obese adipose tissue and atherosclerosis.

27561966

Carcinoma

ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma.

32093682

Carcinoma, Hepatocellular

Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome.

31985234

Carcinoma, Renal Cell

ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma.

32093682

Dehydration

Importance of inositols and their derivatives in cowpea under root dehydration: An omics perspective.

33247842

Diabetes Mellitus, Type 2

Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.

25099943

Metabolic Diseases

Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease.

10971205

Neoplasm Metastasis

Co-expression network analysis identified six hub genes in association with metastasis risk and prognosis in hepatocellular carcinoma.

28430663

Neoplasms

ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma.

32093682

Neoplasms

HSP27, ALDH6A1 and Prohibitin Act as a Trio-biomarker to Predict Survival in Late Metastatic Prostate Cancer.

30396985

Neoplasms

Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome.

31985234

Prostatic Neoplasms

HSP27, ALDH6A1 and Prohibitin Act as a Trio-biomarker to Predict Survival in Late Metastatic Prostate Cancer.

30396985

html completed