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1.2.1.23: 2-oxoaldehyde dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about 2-oxoaldehyde dehydrogenase (NAD+), go to the full flat file.

Word Map on EC 1.2.1.23

Reaction

a 2-oxoaldehyde
+
NAD+
+
H2O
=
a 2-oxo carboxylate
+
NADH
+
H+

Synonyms

2-ketoaldehyde dehydrogenase, ADH1, alpha-ketoaldehyde dehydrogenase, methylglyoxal dehydrogenase, MGD, NAD+-linked alcohol dehydrogenase 1, NAD+-linked methylglyoxal dehydrogenase, NAD-dependent alpha-ketoaldehyde dehydrogenase, NAD-linked alpha-ketoaldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+)

Expression

Expression on EC 1.2.1.23 - 2-oxoaldehyde dehydrogenase (NAD+)

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
the enzyme activity is highly induced in glutathione GSH-deficient cells