1.2.1.3: aldehyde dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NAD+), go to the full flat file.

Word Map on EC 1.2.1.3

Reaction

an aldehyde
+
NAD+
+
H2O
=
a carboxylate
+
NADH
+
H+

Synonyms

ADH, AdhE, AHD-M1, ALD1A1, ALD4, ALDDH, aldehyde dehydrogenase, aldehyde dehydrogenase (NAD), aldehyde dehydrogenase 1, aldehyde dehydrogenase 1A1, aldehyde dehydrogenase 1A3, aldehyde dehydrogenase 1B1, aldehyde dehydrogenase 2, aldehyde dehydrogenase 3A1, aldehyde dehydrogenase 7A1, aldehyde dehydrogenase class 1, aldehyde dehydrogenase type 2, Aldehyde dehydrogenase [NAD+], Aldehyde dehydrogenase, cytosolic, Aldehyde dehydrogenase, microsomal, aldehyde dehydrogenase-2, aldehyde dehydrogenase7, aldehyde:NAD+ oxidoreductase, ALDH, ALDH 2, ALDH I, ALDH II, ALDH-2, ALDH-E1, ALDH-E2, ALDH1, ALDH1-NL, ALDH1A1, Aldh1a2, Aldh1a3, Aldh1a7, Aldh1b1, ALDH2, ALDH2(1), ALDH2(2), ALDH2(3), ALDH22A1, ALDH2B8, ALDH2C4, ALDH3A1, ALDH3A2, Aldh3b1, ALDH3H1, ALDH5A, ALDH7, Aldh7a1, Aldh8a1, ALDHI, ALDHX, ALHDII, Allergen Alt a 10, aryl-aldehyde dehydrogenases, BADH, benzaldehyde dehydrogenase, Brassica turgor-responsive/drought-induced gene 26 protein, Bt-Aldh, Btg-26, class 1 aldehyde dehydrogenase, class 2 aldehyde dehydrogenase, class I ALDH, CoA-independent aldehyde dehydrogenase, coniferyl-aldehyde dehydrogenase, Cphy_1178, ETA-crystallin, FeaB-K-12, gamma-aminobutyraldehyde dehydrogenase, hALDH2, irreversible NAD+-dependent aldehyde dehydrogenase, K(+)-ACDH, K(+)-activated acetaldehyde dehydrogenase, KGSADH, m-methylbenzaldehyde dehydrogenase, Matured fruit 60 kDa protein, MF-60, Mg(2+)-ACDH, Mg(2+)-activated acetaldehyde dehydrogenase, mitochondrial aldehyde dehydrogenase, NAD+-dependent aldehyde dehydrogenase, NAD+-dependent ALDH, NAD+-linked aldehyde dehydrogenase, NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase, NAD+-specific ALDH, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, Non-lens ALDH1, p-ALDH2, P51, phenylacetaldehyde dehydrogenase, PhnN, phnY, phosphonoacetaldehyde dehydrogenase, phosphonoacetaldehyde oxidase, PM-ALDH9, PnAA dehydrogenase, propionaldehyde dehydrogenase, PuuC, R-aminobutyraldehyde dehydrogenase, RALDH, RALDH(II), RalDH1, Retinal dehydrogenase, retinal dehydrogenase type I, sALDH, salvery aldehyde dehydrogenase, ThnG, Turgor-responsive protein 26G, yALDH, YneI

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.3 aldehyde dehydrogenase (NAD+)

Substrates Products

Substrates Products on EC 1.2.1.3 - aldehyde dehydrogenase (NAD+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2E)-4-hydroxy-2-nonenal + NAD+ + H2O
(2E)-4-hydroxy-2-nonenoic acid + NADH + H+
show the reaction diagram
(E)-2-nonenal + NAD+ + H2O
(E)-non-2-enoate + NADH + H+
show the reaction diagram
-
-
-
-
?
(R)-N-(3-(6-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo[b] thiophene-2-carboxamide + H2O + O2
?
show the reaction diagram
-
i.e. GDC-0834, a Bruton's tyrosine kinase inhibitor, a potential treatment of rheumatoid arthritis. GDC-0834
compound is extensively metabolized by amide hydrolysis by both aldehyde oxidase and carboxylesterase
-
?
(R)-trans-4-hydroxy-2-nonenal + NAD+ + H2O
(2E,4R)-4-hydroxynon-2-enoic acid + NADH + H+
show the reaction diagram
(S)-trans-4-hydroxy-2-nonenal + NAD+ + H2O
(2E,4S)-4-hydroxynon-2-enoic acid + NADH + H+
show the reaction diagram
-
-
-
?
1,3-dihydroxyacetone + NAD+ + H2O
? + NADH + H+
show the reaction diagram
-
53.93% activity compared to acetaldehyde
-
-
?
1-formyl-6-methylpyrene + NAD+
6-methylpyrene 1-carboxylate + NADH + H+
show the reaction diagram
-
-
-
-
?
1-formyl-6-methylpyrene + NAD+ + H2O
6-methylpyrene-1-carboxylic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
1-formyl-8-methylpyrene + NAD+ + H2O
8-methylpyrene-1-carboxylic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
1-formyl-8-methylpyrene + NADP+
8-methylpyrene 1-carboxylate + NADPH + H+
show the reaction diagram
-
-
-
-
?
1-formylpyrene + NAD+
pyrene 1-carboxylate + NADH + H+
show the reaction diagram
-
-
-
-
?
1-formylpyrene + NAD+ + H2O
pyrene-1-carboxylic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
1-naphthaldehyde + NAD+ + H2O
1-naphthoic acid + NADH
show the reaction diagram
46.9% activity compared to p-tolualdehyde
-
-
?
1-naphthaldehyde + NAD+ + H2O
1-naphthoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
2,4-dinitrobenzaldehyde + NAD+ + H2O
2,4-dinitrobenzoate + NADH
show the reaction diagram
-
-
-
-
?
2-chlorobenzaldehyde + NAD+ + H2O
2-chlorobenzoate + NADH + H+
show the reaction diagram
-
28.35% activity compared to formaldehyde
-
-
?
2-formylpyrene + NAD+
pyrene 2-carboxylate + NADH + H+
show the reaction diagram
-
-
-
-
?
2-formylpyrene + NAD+ + H2O
pyrene-2-carboxylic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
2-furaldehyde + NAD+ + H2O
2-furanoic acid + NADH + H+
show the reaction diagram
2-hydroxy-3-nitrobenzaldehyde + NAD+ + H2O
2-hydroxy-3-nitrobenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthalene carboxylate + NADH + H+
show the reaction diagram
-
-
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthoate + NADH
show the reaction diagram
-
-
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthoic acid + NADH
show the reaction diagram
48.8% activity compared to p-tolualdehyde
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
2-nonenal + NAD+ + H2O
(E)-non-2-enoate + NADH + H+
show the reaction diagram
-
-
-
-
?
2-phthalaldehyde + NAD+ + H2O
phthalate + NADH + H+
show the reaction diagram
-
10.81% activity compared to formaldehyde
-
-
?
2-quinolinone-4-carboxaldehyde + NAD+ + H2O
2-quinolinone-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
3,4,5-trimethoxybenzaldehyde + NAD+ + H2O
3,4,5-trimethoxybenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
3,4-dihydroxybenzaldehyde + NAD+ + H2O
3,4-dihydroxybenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
3,4-dihydroxymandelic aldehyde + NAD+ + H2O
3,4-dihydroxymandelate + NADH
show the reaction diagram
-
-
-
-
?
3,4-dihydroxyphenyl acetaldehyde + NAD+ + H2O
3,4-dihydroxyphenylacetate + NADH
show the reaction diagram
-
-
-
-
?
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O
3,4-dihydroxyphenylacetate + NADH + H+
show the reaction diagram
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O
3,4-dihydroxyphenylacetic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O
3,4-dihydroxyphenylglycolate + NADH + H+
show the reaction diagram
-
-
-
?
3,4-dimethoxy-5-hydroxybenzaldehyde + NAD+ + H2O
3,4-dimethoxy-5-hydroxybenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
3,4-dimethoxybenzaldehyde + NAD+ + H2O
3,4-dimethoxybenzoate + NADH
show the reaction diagram
-
-
-
-
?
3,4-dimethoxybenzaldehyde + NAD+ + H2O
3,4-dimethoxybenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
3-hydroxy-4-methoxybenzaldehyde + NAD+ + H2O
3-hydroxy-4-methoxybenzoate + NADH + H+
show the reaction diagram
-
-
-
-
?
3-hydroxypropaldehyde + NAD+ + H2O
3-hydroxypropionate + NADH + H+
show the reaction diagram
-
-
-
-
?
3-hydroxypropanal + NAD+ + H2O
3-hydroxypropionate + NADH + H+
show the reaction diagram
3-hydroxypropanoate + NADH + 2 H+
3-hydroxypropionaldehyde + NAD+ + H2O
show the reaction diagram
-
-
-
-
r
3-hydroxypropionaldehyde + NAD+ + H2O
3-hydroxypropanoate + NADH + 2 H+
show the reaction diagram
3-hydroxypropionaldehyde + NAD+ + H2O
3-hydroxypropionic acid + NADH + H+
show the reaction diagram
3-methoxy-4-hydroxyphenylacetaldehyde + NAD+ + H2O
3-methoxy-4-hydroxyphenylacetate + NADH + H+
show the reaction diagram
-
-
-
-
?
3-nitrobenzaldehyde + NAD+ + H2O
3-nitrobenzoate + NADH + H+
show the reaction diagram
-
32.98% activity compared to acetaldehyde
-
-
?
3-oxopropyl phosphonate + NAD+ + H2O
?
show the reaction diagram
-
-
-
-
?
3-oxopropylphosphonate + NAD+ + H2O
?
show the reaction diagram
-
-
-
?
3-pyridinecarboxaldehyde + NAD+ + H2O
3-pyridinecarboxylate + NADH
show the reaction diagram
-
-
-
-
?
4-aminobutyraldehyde + NAD+ + H2O
4-aminobutyrate + NADH
show the reaction diagram
-
-
-
-
?
4-carboxybenzaldehyde + NAD+ + H2O
4-carboxybenzoate + NADH
show the reaction diagram
-
-
-
-
?
4-chlorobenzaldehyde + NAD+ + H2O
4-chlorobenzoate + NADH
show the reaction diagram
-
-
-
-
?
4-chlorophenylacetaldehyde + NAD+ + H2O
4-chlorophenylacetate + NADH + H+
show the reaction diagram
-
-
-
-
?
4-cyanobenzaldehyde + NAD+ + H2O
4-cyanobenzoate + NADH
show the reaction diagram
-
-
-
-
?
4-dimethylamino-1-naphthaldehyde + NAD+ + H2O
4-dimethylamino-1-naphthoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
4-dimethylaminobenzaldehyde + NAD+ + H2O
4-dimethylaminobenzoate + NADH + H+
show the reaction diagram
-
-
-
-
?
4-fluorophenylacetaldehyde + NAD+ + H2O
4-fluorophenylacetate + NADH + H+
show the reaction diagram
-
-
-
-
?
4-formylpyrene + NAD+
pyrene 4-carboxylate + NADH + H+
show the reaction diagram
-
-
-
-
?
4-formylpyrene + NAD+ + H2O
pyrene-4-carboxylic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
4-hydroxy-2-nonenal + NAD+ + H2O
4-hydroxy-2-nonenoate + NADH + H+
show the reaction diagram
4-hydroxy-2-nonenal + NAD+ + H2O
4-hydroxynon-2-enoate + NADH + H+
show the reaction diagram
-
-
-
-
?
4-hydroxy-2-nonenal + NAD+ + H2O
4-hydroxynon-2-enoic acid + NADH
show the reaction diagram
4-hydroxy-3,5-dimethoxybenzaldehyde + NAD+ + H2O
4-hydroxy-3,5-dimethoxybenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O
4-hydroxy-3-methoxybenzoate + NADH + H+
show the reaction diagram
-
-
-
-
?
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O
4-hydroxy-3-methoxybenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
4-hydroxybenzaldehyde + NAD+ + H2O
4-hydroxybenzoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
4-hydroxynon-2-enal + NAD+
4-hydroxynon-2-enoic acid + NADH
show the reaction diagram
-
-
-
-
?
4-hydroxynonenal + NAD+ + H2O
4-hydroxynonanoate + NADH
show the reaction diagram
-
-
-
-
?
4-hydroxynonenal + NAD+ + H2O
4-hydroxynonaoate + NADH
show the reaction diagram
-
-
-
-
?
4-hydroxynonenal + NAD+ + H2O
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-hydroxyphenyl-3-methoxyglycolaldehyde + NAD+ + H2O
4-hydroxyphenyl-3-methoxyglycolate + NADH
show the reaction diagram
-
-
-
-
?
4-hydroxyphenylglycolaldehyde + NAD+ + H2O
4-hydroxyphenylglycolate + NADH
show the reaction diagram
-
-
-
-
?
4-methoxy-1-naphthaldehyde + NAD+ + H2O
4-methoxy-1-naphthoate + NADH
show the reaction diagram
-
-
-
-
?
4-methoxy-1-naphthaldehyde + NAD+ + H2O
4-methoxy-1-naphthoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
4-methoxybenzaldehyde + NAD+ + H2O
4-methoxybenzoate + NADH + H+
show the reaction diagram
-
-
-
-
?
4-nitro-1-naphthaldehyde + NAD+ + H2O
4-nitro-1-naphthoate + NADH
show the reaction diagram
-
-
-
-
?
4-oxonon-2-enal + NAD+ + H2O
4-oxonon-2-enoic acid + NADH
show the reaction diagram
-
-
-
-
?
5-bromo-1-naphthaldehyde + NAD+ + H2O
5-bromo-1-naphthoate + NADH
show the reaction diagram
-
-
-
-
?
5-hydroxyindol acetaldehyde + NAD+ + H2O
5-hydroxyindol acetate + NADH
show the reaction diagram
-
-
-
-
?
5-methoxyindole-3-carboxaldehyde + NAD+ + H2O
5-methoxyindole-3-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
6,7-dimethoxycoumarin-4-carboxaldehyde + NAD+ + H2O
6,7-dimethoxycoumarin-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
6-(dimethylamino)-2-naphthaldehyde + NAD+ + H2O
6-(dimethylamino)-2-naphthoate + NADH
show the reaction diagram
-
-
-
-
?
6-dimethylamino-2-naphthaldehyde + NAD+ + H2O
6-dimethylamino-2-naphthalene carboxylate + NADH + H+
show the reaction diagram
-
activity assay
-
-
?
6-dimethylamino-2-naphthaldehyde + NAD+ + H2O
6-dimethylamino-2-naphthoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
6-methoxy-2-naphthaldehyde + NAD+ + H2O
6-methoxy-2-naphthalene carboxylate + NADH + H+
show the reaction diagram
-
activity assay
-
-
?
6-methoxy-2-naphthaldehyde + NAD+ + H2O
6-methoxy-2-naphthoate + NADH + H+
show the reaction diagram
6-methoxy-2-naphthaldehyde + NAD+ + H2O
6-methoxy-2-naphthoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
6-methoxy-2-quinolinone-4-carboxaldehyde + NAD+ + H2O
6-methoxy-2-quinolinone-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
7-(dimethylamino)-2-quinolinone-4-carboxaldehyde + NAD+ + H2O
7-(dimethylamino)-2-quinolinone-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
7-(dimethylamino)coumarin-4-carboxaldehyde + NAD+ + H2O
7-(dimethylamino)coumarin-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
7-acetoxycoumarin-4-carboxaldehyde + NAD+ + H2O
7-acetoxycoumarin-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
7-hydroxycoumarin-4-carboxaldehyde + NAD+ + H2O
7-hydroxycoumarin-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
7-methoxy-1-naphthaldehyde + NAD+ + H2O
7-methoxy-1-naphthoic acid + NADH + H+
show the reaction diagram
7-methoxy-2-quinolinone-4-carboxaldehyde + NAD+ + H2O
7-methoxy-2-quinolinone-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
7-methoxycoumarin-4-carboxaldehyde + NAD+ + H2O
7-methoxycoumarin-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
9-cis retinal + NAD+ + H2O
9-cis retinoic acid + NADH
show the reaction diagram
-
-
-
-
?
9-cis-retinal + NAD+ + H2O
9-cis-retinoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
acetaldehyde + NAD+ + H2O
acetate + NADH + H+
show the reaction diagram
acetaldehyde + NADP+ + H2O
acetate + NADPH + H+
show the reaction diagram
-
low activity with NADP+
-
-
?
acetate + NADH + H+
acetaldehyde + NAD+ + H2O
show the reaction diagram
acrolein + NAD+ + H2O
? + NADH + H+
show the reaction diagram
-
-
-
-
?
aldophosphamide + NAD+ + H2O
? + NADH + H+
show the reaction diagram
-
-
-
-
?
all-trans retinal + NAD+ + H2O
all-trans retinoic acid + NADH
show the reaction diagram
-
-
-
-
?
all-trans-retinal + NAD+ + H2O
all-trans-retinoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
alpha-aminoadipate semialdehyde + NAD+ + H2O
alpha-aminoadipate + NADH + H+
show the reaction diagram
alpha-aminoadipate semialdehyde + NAD+ + H2O
alpha-aminoadipic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
alpha-phenylpropanal + NAD+ + H2O
alpha-phenylpropionate + NADH
show the reaction diagram
-
-
-
-
?
an aldehyde + NAD+ + H2O
an acid + NADH + H+
show the reaction diagram
-
-
-
-
?
anisaldehyde + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
benzaldehyde + NAD(P)+ + H2O
benzoate + NAD(P)H + H+
show the reaction diagram
-
-
-
-
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
show the reaction diagram
benzaldehyde + NADP+
benzoate + NADPH
show the reaction diagram
-
-
-
-
?
benzaldehyde + NADP+ + H2O
benzoate + NADPH + H+
show the reaction diagram
-
-
-
-
?
betaine aldehyde + NAD+ + H2O
betaine + NADH
show the reaction diagram
-
-
-
-
?
betaine aldehyde + NAD+ + H2O
betaine + NADH + H+
show the reaction diagram
-
-
-
-
?
butanal + NAD+ + H2O
butyrate + NADH + H+
show the reaction diagram
butyraldehyde + NAD+ + H2O
butanoate + NADH + H+
show the reaction diagram
-
the activity on butyraldehyde is about 95% of that on valeraldehyde
-
-
?
butyraldehyde + NAD+ + H2O
butanoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
butyraldehyde + NAD+ + H2O
butyrate + NADH + H+
show the reaction diagram
chloral + NAD+ + H2O
trichloroacetate + NADH + H+
show the reaction diagram
-
2.67% activity compared to acetaldehyde
-
-
?
chloroacetaldehyde + NAD+ + H2O
chloroacetate + NADH + H+
show the reaction diagram
cinnamaldehyde + NAD+ + H2O
cinnamate + NADH + H+
show the reaction diagram
cinnamic aldehyde + NAD+ + H2O
cinnamic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
citral + NAD+ + H2O
(2E)-3,7-dimethylocta-2,6-dienoic acid + NADH
show the reaction diagram
-
-
-
-
?
crotonaldehyde + NAD+ + H2O
crotonate + NADH
show the reaction diagram
-
-
-
-
?
cyclohexanaldehyde + NAD+ + H2O
cyclohexanoate + NADH
show the reaction diagram
-
-
-
-
?
D-glucose + NAD+ + H2O
D-glucuronic acid + NADH
show the reaction diagram
-
-
-
-
?
D-glyceraldehyde + NAD+ + H2O
D-glycerate + NADH + H+
show the reaction diagram
-
50.25% activity compared to acetaldehyde
-
-
?
dansyl-aminoacetaldehyde + ?
dansylglycine + ?
show the reaction diagram
-
the fluorescent substrate is used to monitor aldehyde dehydrogenase activity in fluorescence-activated cell sorting
-
-
?
decanal + NAD+ + H2O
decanaote + NADH
show the reaction diagram
-
-
-
-
decanal + NAD+ + H2O
decanoate + NADH
show the reaction diagram
decanaldehyde + NAD+ + H2O
decanoate + NADH + H+
show the reaction diagram
-
50.3% activity compared to formaldehyde
-
-
?
DL-glyceraldehyde + NAD+ + H2O
DL-glycerate + NADH + H+
show the reaction diagram
DL-glyceraldehyde 3-phosphate + NAD+ + H2O
DL-glycerate 3-phosphate + NADH + H+
show the reaction diagram
-
52.7% activity compared to acetaldehyde
-
-
?
dodecanal + NAD+ + H2O
dodecanoate + NADH
show the reaction diagram
-
n-dodecylaldehyde
-
-
?
dodecanal + NAD+ + H2O
dodecanoate + NADH + H+
show the reaction diagram
dodecanaldehyde + NAD+ + H2O
dodecanoate + NADH + H+
show the reaction diagram
-
42.02% activity compared to formaldehyde
-
-
?
eicosanoic aldehyde + NAD+ + H2O
eicosanoate + NADH + H+
show the reaction diagram
-
8.79% activity compared to formaldehyde
-
-
?
fluorene-2-carboxaldehyde + NAD+ + H2O
fluorene-2-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
formaldehyde + NAD+
formate + NADH + H+
show the reaction diagram
-
-
-
-
?
formaldehyde + NAD+ + H2O
formate + NADH
show the reaction diagram
formaldehyde + NAD+ + H2O
formate + NADH + H+
show the reaction diagram
glutaraldehyde + NAD+ + H2O
glutarate + NADH
show the reaction diagram
-
-
-
-
?
glutathione-4-oxonon-2-enal + NAD+ + H2O
glutathione-4-oxonon-2-enoic acid + NADH
show the reaction diagram
-
-
-
-
?
glyceraldehyde + NAD+ + H2O
glycerate + NADH
show the reaction diagram
glyceraldehyde + NAD+ + H2O
glycerate + NADH + H+
show the reaction diagram
glyceraldehyde 3-phosphate + NAD+ + H2O
?
show the reaction diagram
-
-
-
-
?
glyceraldehyde 3-phosphate + NAD+ + H2O
glycerate 3-phosphate + NADH
show the reaction diagram
-
-
-
-
?
glyceraldehyde-3-phosphate + NAD+ + H2O
?
show the reaction diagram
-
-
-
?
glyceryl trinitrate + NADH + H+
1,2-glyceryl dinitrate + nitrite + NAD+
show the reaction diagram
-
-
-
-
?
glyceryl trinitrate + NADH + H+
1,3-glyceryl dinitrate + nitrite + NAD+
show the reaction diagram
-
-
-
-
?
glycolaldehyde + NAD+ + H2O
glycolate + NADH
show the reaction diagram
glycolaldehyde + NAD+ + H2O
glycolate + NADH + H+
show the reaction diagram
-
75.43% activity compared to acetaldehyde
-
-
?
glyoxal + NAD+ + H2O
oxalate + NADH
show the reaction diagram
-
-
-
-
?
heptanal + NAD+ + H2O
heptanoate + NADH
show the reaction diagram
hexadecanal + NAD+ + H2O
hexadecanoate + NADH + H+
show the reaction diagram
-
15.77% activity compared to formaldehyde
-
-
?
hexaldehyde + NAD+ + H2O
hexanoate + NADH + H+
show the reaction diagram
-
76.21% activity compared to formaldehyde
-
-
?
hexanal + NAD+ + H2O
hexanoate + NADH + H+
show the reaction diagram
hexanaldehyde + NAD+ + H2O
hexanoate + NADH + H+
show the reaction diagram
A9KN57
-
-
-
?
hydrocinnamaldehyde + NAD+ + H2O
hydrocinnamate + NADH
show the reaction diagram
-
-
-
-
?
indole-3-acetaldehyde + NAD+ + H2O
indole-3-acetate + NADH + H+
show the reaction diagram
indole-3-aldehyde + NAD+ + H2O
indole-3-carboxylate + NADH
show the reaction diagram
isobutanal + NAD+ + H2O
isobutyrate + NADH
show the reaction diagram
-
-
-
-
?
isovaleraldehyde + NAD+ + H2O
isovalerate + NADH + H+
show the reaction diagram
m-chlorobenzaldehyde + NAD+ + H2O
m-chlorobenzoic acid + NADH + H+
show the reaction diagram
44.7% activity compared to p-tolualdehyde
-
-
?
m-fluorobenzaldehyde + NAD+ + H2O
m-fluorobenzoic acid + NADH + H+
show the reaction diagram
m-hydroxybenzaldehyde + NAD+ + H2O
m-hydroxybenzoate + NADH + H+
show the reaction diagram
-
-
-
-
?
m-hydroxybenzaldehyde + NAD+ + H2O
m-hydroxybenzoic acid + NADH + H+
show the reaction diagram
23.6% activity compared to p-tolualdehyde
-
-
?
m-methoxybenzaldehyde + NAD+ + H2O
m-methoxybenzoate + NADH + H+
show the reaction diagram
m-methoxybenzaldehyde + NAD+ + H2O
m-methoxybenzoic acid + NADH + H+
show the reaction diagram
88.5% activity compared to p-tolualdehyde
-
-
?
m-methylbenzaldehyde + NAD+ + H2O
m-methylbenzoate + NADH
show the reaction diagram
-
-
-
-
?
m-nitrobenzaldehyde + NAD+ + H2O
m-nitrobenzoate + NADH
show the reaction diagram
m-nitrobenzaldehyde + NAD+ + H2O
m-nitrobenzoic acid + NADH
show the reaction diagram
46.8% activity compared to p-tolualdehyde
-
-
?
m-tolualdehyde + NAD+ + H2O
m-methylbenzoic acid + NADH
show the reaction diagram
70.8% activity compared to p-tolualdehyde
-
-
?
malondialdehyde + NAD+ + H2O
?
show the reaction diagram
malondialdehyde + NAD+ + H2O
? + NADH
show the reaction diagram
malondialdehyde + NAD+ + H2O
? + NADH + H+
show the reaction diagram
-
-
-
-
?
methylglyoxal + NAD+ + H2O
methylglyoxalate + NADH
show the reaction diagram
-
-
-
-
?
monochloroacetaldehyde + NAD+ + H2O
monochloroacetate + NADH
show the reaction diagram
-
-
-
-
?
N-acetyl-4-aminobutyraldehyde + NAD+ + H2O
N-acetyl-4-aminobutyrate + NADH
show the reaction diagram
-
-
-
-
?
n-nonanal + NAD+ + H2O
n-nonanoate + NADH + H+
show the reaction diagram
nitroglycerin + NAD+ + H2O
1,2-glyceryl dinitrate + NO + NADH + H+
show the reaction diagram
-
-
-
-
?
nonanal + NAD+ + H2O
nonanoate + NADH + H+
show the reaction diagram
o-chlorobenzaldehyde + NAD+ + H2O
o-chlorobenzoic acid + NADH + H+
show the reaction diagram
3.4% activity compared to p-tolualdehyde
-
-
?
o-fluorobenzaldehyde + NAD+ + H2O
o-fluorobenzoic acid + NADH + H+
show the reaction diagram
o-hydroxybenzaldehyde + NAD+ + H2O
o-hydroxybenzoate + NADH + H+
show the reaction diagram
-
-
-
-
?
o-hydroxybenzaldehyde + NAD+ + H2O
o-hydroxybenzoic acid + NADH + H+
show the reaction diagram
65.2% activity compared to p-tolualdehyde
-
-
?
o-methoxybenzaldehyde + NAD+ + H2O
o-methoxybenzoate + NADH + H+
show the reaction diagram
-
-
-
-
?
o-methoxybenzaldehyde + NAD+ + H2O
o-methoxybenzoic acid + NADH + H+
show the reaction diagram
2.6% activity compared to p-tolualdehyde
-
-
?
o-methylbenzaldehyde + NAD+ + H2O
o-methylbenzoate + NADH
show the reaction diagram
-
-
-
-
?
o-nitrobenzaldehyde + NAD+ + H2O
o-nitrobenzoate + NADH
show the reaction diagram
-
-
-
-
?
o-nitrobenzaldehyde + NAD+ + H2O
o-nitrobenzoic acid + NADH
show the reaction diagram
17.8% activity compared to p-tolualdehyde
-
-
?
o-tolualdehyde + NAD+ + H2O
o-methylbenzoic acid + NADH
show the reaction diagram
3.7% activity compared to p-tolualdehyde
-
-
?
octadecanal + NAD+ + H2O
octadecanoate + NADH + H+
show the reaction diagram
-
12% activity compared to formaldehyde
-
-
?
octanal + NAD+ + H2O
octanoate + NADH
show the reaction diagram
octanal + NAD+ + H2O
octanoate + NADH + H+
show the reaction diagram
octyl aldehyde + NAD+ + H2O
octanoate + NADH + H+
show the reaction diagram
-
72.27% activity compared to formaldehyde
-
-
?
p-(dimethylamino)-benzaldehyde + NAD+ + H2O
p-(dimethylamino)benzoate + NADH
show the reaction diagram
-
-
-
-
?
p-(dimethylamino)cinnamaldehyde + NAD+ + H2O
p-(dimethylamino)cinnamate + NADH
show the reaction diagram
p-carboxybenzaldehyde + NAD+ + H2O
p-carboxybenzoate + NADH
show the reaction diagram
-
-
-
-
?
p-chlorobenzaldehyde + NAD+ + H2O
p-chlorobenzoic acid + NADH + H+
show the reaction diagram
79.6% activity compared to p-tolualdehyde
-
-
?
p-fluorobenzaldehyde + NAD+ + H2O
p-fluorobenzoic acid + NADH + H+
show the reaction diagram
p-hydroxybenzaldehyde + NAD+ + H2O
p-hydroxybenzoic acid + NADH + H+
show the reaction diagram
4.2% activity compared to p-tolualdehyde
-
-
?
p-hydroxyphenylacetaldehyde + NAD+ + H2O
p-hydroxyphenylacetate + NADH
show the reaction diagram
p-methoxybenzaldehyde + NAD+ + H2O
p-methoxybenzoate + NADH + H+
show the reaction diagram
p-methoxybenzaldehyde + NAD+ + H2O
p-methoxybenzoic acid + NADH + H+
show the reaction diagram
6.2% activity compared to p-tolualdehyde
-
-
?
p-methylbenzaldehyde + NAD+ + H2O
p-methylbenzoate + NADH
show the reaction diagram
-
-
-
-
?
p-nitrobenzaldehyde + NAD+ + H2O
p-nitrobenzoate + NADH
show the reaction diagram
p-nitrobenzaldehyde + NAD+ + H2O
p-nitrobenzoic acid + NADH
show the reaction diagram
69% activity compared to p-tolualdehyde
-
-
?
p-nitrocinnamaldehyde + NAD+ + H2O
p-nitrocinnamate + NADH
show the reaction diagram
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
-
esterase activity of the various isoenzymes is less than 7% of the activity with propanal and NAD+
-
-
?
p-tolualdehyde + NAD+ + H2O
p-methylbenzoic acid + NADH
show the reaction diagram
highest activity
-
-
?
pentanal + NAD+ + H2O
pentanoate + NADH
show the reaction diagram
pentanaldehyde + NAD+ + H2O
pentanoate + NADH + H+
show the reaction diagram
A9KN57
-
-
-
?
phenanthrene-9-carboxaldehyde + NAD+ + H2O
phenanthrene-9-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
phenylacetaldehyde + NAD+ + H2O
phenylacetate + NADH + H+
show the reaction diagram
phosphonoacetaldehyde + NAD+
?
show the reaction diagram
-
-
-
-
?
phosphonoacetaldehyde + NAD+ + H2O
phosphonoacetate + NADH + H+
show the reaction diagram
pimelic semialdehyde + NAD+ + H2O
?
show the reaction diagram
pivaldehyde + NAD+ + H2O
pivalate + NADH
show the reaction diagram
-
-
-
-
?
propanal + 1,N6-ethenoadenine dinucleotide + H2O
propionate + ?
show the reaction diagram
-
isoenzyme E3
-
-
?
propanal + 3-acetylpyridine-adenine dinucleotide + H2O
propionate + ?
show the reaction diagram
-
isoenzyme E3
-
-
?
propanal + 3-acetylpyridine-NAD+ + H2O
propionate + 3-acetylpyridine-NADH
show the reaction diagram
-
-
-
-
?
propanal + 3-thionicotinamide-adenine dinucleotide + H2O
propionate + ?
show the reaction diagram
-
isoenzyme E3
-
-
?
propanal + deamino-NAD+ + H2O
propionate + deamino-NADH
show the reaction diagram
-
-
-
-
?
propanal + N-guanine dinucleotide + H2O
propionate + ?
show the reaction diagram
-
isoenzyme E3
-
-
?
propanal + NAD+ + H2O
propanoate + NADH + H+
show the reaction diagram
propanal + NAD+ + H2O
propanoic acid + NADH + H+
show the reaction diagram
-
activity assay
-
-
?
propanal + NAD+ + H2O
propionate + NADH
show the reaction diagram
propanal + NAD+ + H2O
propionate + NADH + H+
show the reaction diagram
propanal + oxidized nicotinamide hypoxanthine dinucleotide + H2O
propionate + reduced nicotinamide hypoxanthine dinucleotide
show the reaction diagram
-
isoenzyme E3
-
-
?
propanal + [5-(3-acetylpyridino)pentyl]diphosphoadenosine + H2O
propanoate + ?
show the reaction diagram
-
-
-
-
?
propionaldehyde + NAD+
propionate + NADH + H+
show the reaction diagram
-
-
-
-
?
propionaldehyde + NAD+ + H2O
propanoate + NADH + H+
show the reaction diagram
propionaldehyde + NAD+ + H2O
propanoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
propionaldehyde + NAD+ + H2O
propionate + NADH
show the reaction diagram
-
-
-
-
?
propionaldehyde + NAD+ + H2O
propionate + NADH + H+
show the reaction diagram
protocatechaldehyde + NAD+ + H2O
protocatechuic acid + NADH
show the reaction diagram
4.5% activity compared to p-tolualdehyde
-
-
?
pyridine 3-aldehyde + NAD+ + H2O
pyridine-3-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
pyridine-3-aldehyde adenine dinucleotide + NAD+ + H2O
pyridine-3-carboxylate adenine dinucleotide + NADH
show the reaction diagram
-
-
-
-
?
pyruvic aldehyde + NAD+ + H2O
pyruvate + NADH
show the reaction diagram
-
-
-
-
?
quinoline-3-carboxaldehyde + NAD+ + H2O
quinoline-3-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
quinoline-4-carboxaldehyde + NAD+ + H2O
quinoline-4-carboxylate + NADH
show the reaction diagram
-
-
-
-
?
retinal + NAD+ + H2O
retinoic acid + NADH + H+
show the reaction diagram
-
-
-
?
retinol + NAD+ + H2O
retinoic acid + NADH + H+
show the reaction diagram
-
-
-
-
?
succinic semialdehyde + NAD+ + H2O
succinate + NADH
show the reaction diagram
syringaldehyde + NAD+ + H2O
syringic acid + NADH
show the reaction diagram
65.1% activity compared to p-tolualdehyde
-
-
?
tetradecanal + NAD+ + H2O
tetradecanoate + NADH
show the reaction diagram
tetradecyl aldehyde + NAD+ + H2O
tetradecanoate + NADH + H+
show the reaction diagram
-
11.71% activity compared to formaldehyde
-
-
?
trans-2-hexenal + NAD+ + H2O
(E)-hex-2-enoate + NADH + H+
show the reaction diagram
trans-2-nonenal + NAD+ + H2O
(E)-non-2-enoate + NADH + H+
show the reaction diagram
-
-
-
?
trans-cinnamaldehyde + NAD+ + H2O
trans-cinnamate + NADH
show the reaction diagram
valeraldehyde + NAD+ + H2O
valerate + NADH + H+
show the reaction diagram
vanillin + NAD+ + H2O
vanillic acid + NADH + H+
show the reaction diagram
additional information
?
-