1.2.1.30: carboxylate reductase (NADP+)
This is an abbreviated version!
For detailed information about carboxylate reductase (NADP+), go to the full flat file.
Word Map on EC 1.2.1.30 
Reaction
an aromatic aldehyde +
NADP+ +
AMP +
diphosphate=
an aromatic acid +
NADPH +
H+ +
ATP
Synonyms
aromatic acid reductase, aryl aldehyde:NADP+ oxidoreductase, aryl-aldehyde dehydrogenase (NADP+), aryl-aldehyde oxidoreductase, ATP/NADPH-dependent carboxylic acid reductase, CAR, carboxylate reductase, carboxylate reductases, Carboxylic acid reductase, kaCAR, mab3CAR, maCAR, mmCAR, mpCAR, msCAR, naCAR, NcCAR, niCAR, noCAR, tpCAR, type I CAR, type III CAR
ECTree
KM Value
KM Value on EC 1.2.1.30 - carboxylate reductase (NADP+)
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0.05 - 0.72
(E)-3-phenylprop-2-enoate
-
0.0345
(R)-ibuprofen
Nocadia sp.
-
-
9
2-Methoxybenzoate
-
pH 7.8, 30°C
0.56 - 12
3-Methoxybenzoate
0.3 - 5.6
3-Nitrobenzoate
0.27 - 3.8
3-oxo-3-phenylpropanoate
0.09 - 1.3
3-phenylprop-2-ynoate
-
0.16 - 3
3-Phenylpropionate
0.19 - 2.8
4-Methoxybenzoate
0.16 - 3.7
4-Methylbenzoate
0.6
4-nitrobenzoate
-
pH 7.8, 30°C
0.362
benzoic acid
pH and temperature not specified in the publication
0.2
benzoyladenosine 5'-monophosphate
-
-
4.7 - 13
furan-2-carboxylate
0.155
Ibuprofen
Nocadia sp.
-
-
20 - 24
pyridine-2-carboxylate
1 - 50
Thiophene-2-carboxylate
0.006 - 1.8
trans-2-phenylcyclopropane-1-carboxylate
-
additional information
additional information
-
0.05
(E)-3-phenylprop-2-enoate
pH 7.5, 30°C
-
0.075
(E)-3-phenylprop-2-enoate
-
pH 8.0, 30°C
-
0.3
(E)-3-phenylprop-2-enoate
-
pH 7.3, 30°C
-
0.31
(E)-3-phenylprop-2-enoate
-
pH 7.8, 30°C
-
0.72
(E)-3-phenylprop-2-enoate
-
pH 7.5, 30°C
-
0.56
3-Methoxybenzoate
-
pH 7.8, 30°C
0.68
3-Methoxybenzoate
pH 7.5, 30°C
0.9
3-Methoxybenzoate
-
pH 7.5, 30°C
3
3-Methoxybenzoate
-
pH 7.3, 30°C
12
3-Methoxybenzoate
-
pH 7.8, 30°C
0.3
3-Nitrobenzoate
-
pH 7.3, 30°C
0.5
3-Nitrobenzoate
-
pH 7.8, 30°C
0.7
3-Nitrobenzoate
-
pH 7.8, 30°C
2.5
3-Nitrobenzoate
-
pH 7.5, 30°C
5.6
3-Nitrobenzoate
pH 7.5, 30°C
0.27
3-oxo-3-phenylpropanoate
-
pH 8.0, 30°C
0.29
3-oxo-3-phenylpropanoate
-
pH 7.5, 30°C
0.39
3-oxo-3-phenylpropanoate
pH 7.5, 30°C
0.55
3-oxo-3-phenylpropanoate
-
pH 7.8, 30°C
3.8
3-oxo-3-phenylpropanoate
-
pH 7.3, 30°C
0.09
3-phenylprop-2-ynoate
-
pH 7.8, 30°C
-
1.3
3-phenylprop-2-ynoate
pH 7.5, 30°C
-
0.16
3-Phenylpropionate
-
pH 8.0, 30°C
0.32
3-Phenylpropionate
-
pH 7.8, 30°C
0.97
3-Phenylpropionate
pH 7.5, 30°C
2.7
3-Phenylpropionate
-
pH 7.5, 30°C
3
3-Phenylpropionate
-
pH 7.3, 30°C
0.19
4-Methoxybenzoate
-
pH 7.8, 30°C
0.25
4-Methoxybenzoate
pH 7.5, 30°C
0.45
4-Methoxybenzoate
-
pH 7.8, 30°C
1.1
4-Methoxybenzoate
-
pH 7.5, 30°C
2.8
4-Methoxybenzoate
-
pH 7.3, 30°C
0.16
4-Methylbenzoate
-
pH 7.8, 30°C
0.69
4-Methylbenzoate
-
pH 7.8, 30°C
1
4-Methylbenzoate
pH 7.5, 30°C
1.2
4-Methylbenzoate
-
pH 7.5, 30°C
3.7
4-Methylbenzoate
-
pH 7.3, 30°C
0.0573
ATP
Nocadia sp.
-
-
0.115
ATP
pH and temperature not specified in the publication
0.063
benzoate
-
-
0.645
benzoate
Nocadia sp.
-
-
0.9
benzoate
pH 7.5, 30°C
2
benzoate
-
pH 7.8, 30°C
2.1
benzoate
-
pH 7.5, 30°C
3.4
benzoate
-
pH 7.8, 30°C
20
benzoate
-
pH 7.3, 30°C
5
Butanoate
-
pH 7.8, 30°C
7.9
Butanoate
-
pH 8.0, 30°C
32
Butanoate
pH 7.5, 30°C
50
Butanoate
-
pH 7.5, 30°C
0.02
dodecanoate
pH 7.5, 30°C
0.04
dodecanoate
-
pH 7.5, 30°C
0.04
dodecanoate
-
pH 7.8, 30°C
0.05
dodecanoate
-
pH 8.0, 30°C
0.09
dodecanoate
-
pH 7.3, 30°C
4.7
furan-2-carboxylate
-
pH 7.8, 30°C
13
furan-2-carboxylate
-
pH 8.0, 30°C
0.0293
NADPH
Nocadia sp.
-
-
0.048
NADPH
pH and temperature not specified in the publication
0.13
NADPH
-
reduction of the intermediate benzoyladenylate to benzaldehyde
0.02
octadecanoate
-
pH 7.5, 30°C
0.02
octadecanoate
-
pH 7.8, 30°C
0.09
octadecanoate
-
pH 7.3, 30°C
0.6
octadecanoate
-
pH 8.0, 30°C
0.7
octadecanoate
pH 7.5, 30°C
0.1
Octanoate
-
pH 8.0, 30°C
0.2
Octanoate
-
pH 7.5, 30°C
0.2
Octanoate
pH 7.5, 30°C
0.2
Octanoate
-
pH 7.8, 30°C
2
Octanoate
-
pH 7.3, 30°C
20
pyridine-2-carboxylate
-
pH 7.5, 30°C
24
pyridine-2-carboxylate
-
pH 7.8, 30°C
1
Thiophene-2-carboxylate
pH 7.5, 30°C
2.6
Thiophene-2-carboxylate
-
pH 7.5, 30°C
3.3
Thiophene-2-carboxylate
-
pH 8.0, 30°C
3.3
Thiophene-2-carboxylate
-
pH 7.8, 30°C
50
Thiophene-2-carboxylate
-
pH 7.3, 30°C
0.006
trans-2-phenylcyclopropane-1-carboxylate
-
pH 8.0, 30°C
-
0.061
trans-2-phenylcyclopropane-1-carboxylate
-
pH 7.8, 30°C
-
0.21
trans-2-phenylcyclopropane-1-carboxylate
pH 7.5, 30°C
-
1
trans-2-phenylcyclopropane-1-carboxylate
-
pH 7.5, 30°C
-
1.8
trans-2-phenylcyclopropane-1-carboxylate
-
pH 7.3, 30°C
-
additional information
additional information
-
kinetic analysis
-
additional information
additional information
-
kinetic analysis
-
additional information
additional information
-
kinetic analysis
-
additional information
additional information
-
kinetic analysis
-
additional information
additional information
kinetic analysis
-
additional information
additional information
-
stopped-flow measurements, steady-state (kcat) and single-turnover (kobs) kinetics of wild-type and hybrid mutant enzymes, comparisons, overview
-
additional information
additional information
-
stopped-flow measurements, steady-state (kcat) and single-turnover (kobs) kinetics of wild-type and hybrid mutant enzymes, comparisons, overview
-
additional information
additional information
-
stopped-flow measurements, steady-state (kcat) and single-turnover (kobs) kinetics of wild-type and hybrid mutant enzymes, comparisons, overview
-
additional information
additional information
-
stopped-flow measurements, steady-state (kcat) and single-turnover (kobs) kinetics of wild-type and hybrid mutant enzymes, comparisons, overview
-
additional information
additional information
stopped-flow measurements, steady-state (kcat) and single-turnover (kobs) kinetics of wild-type and hybrid mutant enzymes, comparisons, overview
-
1.2.1.30 carboxylate reductase (NADP+)
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