1.2.1.30: carboxylate reductase (NADP+)

This is an abbreviated version!
For detailed information about carboxylate reductase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.30

1.2.1.30

synthesis

bio-based

fragrance

autoinduction

phosphopantetheinylation

over-reduction

benzaldehyde

industry

Reaction

Synonyms

aromatic acid reductase, aryl aldehyde:NADP+ oxidoreductase, aryl-aldehyde dehydrogenase (NADP+), aryl-aldehyde oxidoreductase, ATP/NADPH-dependent carboxylic acid reductase, CAR, carboxylate reductase, carboxylate reductases, Carboxylic acid reductase, kaCAR, mab3CAR, maCAR, mmCAR, mpCAR, msCAR, naCAR, NcCAR, niCAR, noCAR, tpCAR, type I CAR, type III CAR

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.30 carboxylate reductase (NADP+)

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Results	in table
11	Activating Compound
9	AA Sequence
37	Application
1	CAS Registry Number
22	Cloned(Commentary)
81	Cofactor
93	General Information
1	General Stability
43	Inhibitors
84	kcat/KM [mM/s]
6	Ki Value [mM]
100	KM Value [mM]
25	Metals/Ions
6	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
75	Organism
3	PDB ID
14	pH Optimum
1	pH Range
1	pI Value
22	Posttranslational Modification
84	Protein Variants
12	Purification (Commentary)
36	Reaction
3	Reaction Type
61	Reference
4	Source Tissue
11	Specific Activity [micromol/min/mg]
5	Storage Stability
294	Substrates and Products (Substrate)
25	Subunits
137	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]
11	Temperature Stability [°C]
77	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.2.1.30 - carboxylate reductase (NADP+)

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0.008

induced cells

0.035

induced cells

0.11

pH 7.5, 25°C, recombinant enzyme with His-tag

654277

0.3

Nocardia iowensis

recombinant car incubated with CoA

693019

0.36

Nocardia iowensis

Q6RKB1

recombinant Car expressed in Escherichia coli BL21-CodonPlus(DE3)-RP cells cultured in LB medium with ampicillin, at 16 h

692118

0.5

Nocardia iowensis

Nocardia cell free extract incubated with recombinant car

0.864

1.5

recombinant car incubated with CoA and Escherichia coli MV1190/pUC8-sfp cell free extract

693019

1.6

Nocardia iowensis

Nocardia cell free extract incubated with recombinant car and CoA. Recombinant car incubated with CoA and Npt

693019

2.1

Nocardia iowensis

car purified from BL21-CodonPlus(DE3)-RP/pPV1.184 (car and sfp)

693019

5.89

Nocadia sp.

purified enzyme

288184