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1.2.1.4: aldehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.4

Reaction

an aldehyde
+
NADP+
+
H2O
=
a carboxylate
+
NADPH
+
H+

Synonyms

AKR1A4, ALD6, aldehyde dehydrogenase (NADP+), aldehyde dehydrogenase 3A1, aldehyde dehydrogenase 6, aldehyde reductase, ALDH, ALDH1, ALDH1F1, ALDH3A1, ALDH6, AlDHPyr1147, dehydrogenase, aldehyde (nicotinamide adenine dinucleotide phosphate), Kvbeta2, NADP dependent aldehyde dehydrogenase, NADP+-dependent Ald6, NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, Seegmiller enzyme, Ta0439, TaAlDH

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.4 aldehyde dehydrogenase (NADP+)

Disease

Disease on EC 1.2.1.4 - aldehyde dehydrogenase (NADP+)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinoma, Hepatocellular
Comparative subcellular distribution of benzaldehyde and acetaldehyde dehydrogenase activities in two hepatoma cell lines and in normal hepatocytes.
Oxidative metabolism of 4-hydroxy-2,3-nonenal during diethyl-nitrosamine-induced carcinogenesis in rat liver.
Demyelinating Diseases
Potassium channel distribution, clustering, and function in remyelinating rat axons.
Neoplasms
Aldehyde dehydrogenases and cell proliferation.
Molecular organization of the Escherichia coli gab cluster: nucleotide sequence of the structural genes gabD and gabP and expression of the GABA permease gene.
Retinoic acid biosynthesis by normal human breast epithelium is via aldehyde dehydrogenase 6, absent in MCF-7 cells.