1.2.1.4: aldehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.4

Reaction

an aldehyde
+
NADP+
+
H2O
=
a carboxylate
+
NADPH
+
H+

Synonyms

AKR1A4, aldehyde dehydrogenase (NADP+), aldehyde dehydrogenase 3A1, aldehyde reductase, ALDH, ALDH1, ALDH3A1, AlDHPyr1147, dehydrogenase, aldehyde (nicotinamide adenine dinucleotide phosphate), Kvbeta2, NADP dependent aldehyde dehydrogenase, NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, Seegmiller enzyme

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.4 aldehyde dehydrogenase (NADP+)

KM Value

KM Value on EC 1.2.1.4 - aldehyde dehydrogenase (NADP+)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.9
4-hydroperoxycyclophosphamide
-
pH 7.5, 25°C
0.045 - 0.056
4-hydroxy-2-nonenal
0.0025 - 35
acetaldehyde
0.056 - 2.1
benzaldehyde
0.98 - 2.2
Butanal
0.15
Butyraldehyde
-
pH 8.4, 28°C, cosubstrate NADP+
0.0036
Chloroacetaldehyde
-
pH 7.5, 25°C
0.0015 - 0.023
decanal
0.01
dodecanal
-
-
0.38 - 4.2
formaldehyde
0.11
Glutaraldehyde
-
pH 8.4, 28°C, cosubstrate NADP+
0.65 - 15
glyceraldehyde
2.2
glycolaldehyde
-
-
0.055 - 0.108
Heptanal
0.25 - 0.46
hexanal
20
Isobutyraldehyde
at pH 8.8 and 60°C
0.03
isopentanal
-
-
0.015
muconaldehyde
-
1.26
NAD+
-
pH 8.4, 28°C, cosubstrate butyraldehyde
0.0022 - 0.21
NADP+
0.0039 - 0.025
Nonanal
0.0093 - 0.062
octanal
0.435 - 0.92
pentanal
0.0058 - 11
propanal
1.5 - 21
propionaldehyde
0.015
Tetradecanal
-
-
0.155
trans-2-hexenal
0.012
trans-2-nonenal
0.035
trans-2-octenal
0.023
tridecanal
-
-
0.016
Undecanal
-
-
additional information
additional information
-