1.2.1.4: aldehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.4

Reaction

an aldehyde
+
NADP+
+
H2O
=
a carboxylate
+
NADPH
+
H+

Synonyms

AKR1A4, aldehyde dehydrogenase (NADP+), aldehyde dehydrogenase 3A1, aldehyde reductase, ALDH, ALDH1, ALDH3A1, AlDHPyr1147, dehydrogenase, aldehyde (nicotinamide adenine dinucleotide phosphate), Kvbeta2, NADP dependent aldehyde dehydrogenase, NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, Seegmiller enzyme

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.4 aldehyde dehydrogenase (NADP+)

Purification

Purification on EC 1.2.1.4 - aldehyde dehydrogenase (NADP+)

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
aldehyde dehydrogenase a, b, c, d, and e
-
Ni-NTA column chromatography
-
nickel affinity column chromatography
-
Source 30Q column chromatography and Superdex 200 gel filtration
using a Q-sepharose anion exchange column for enzyme preparation of mouse liver, using nickel agarose affinity chromatography for purification of recombinant protein