1.2.1.4: aldehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.4

Reaction

an aldehyde
+
NADP+
+
H2O
=
a carboxylate
+
NADPH
+
H+

Synonyms

AKR1A4, aldehyde dehydrogenase (NADP+), aldehyde dehydrogenase 3A1, aldehyde reductase, ALDH, ALDH1, ALDH3A1, AlDHPyr1147, dehydrogenase, aldehyde (nicotinamide adenine dinucleotide phosphate), Kvbeta2, NADP dependent aldehyde dehydrogenase, NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, Seegmiller enzyme

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.4 aldehyde dehydrogenase (NADP+)

Reference

Reference on EC 1.2.1.4 - aldehyde dehydrogenase (NADP+)

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vandecasteele, J.P.; Guerrillot, L.
Aldehyde dehydrogenases from Pseudomonas aeruginosa
Methods Enzymol.
89
484-490
1982
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Guerrillot, L.; Vandecasteele, J.P.
Purification and characterization of two aldehyde dehydrogenases from Pseudomonas aeruginosa
Eur. J. Biochem.
81
185-192
1977
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Hommel, R.; Kurth, J.; Kleber, H.P.
NADP+-dependent aldehyde dehydrogenase from Acetobacter rancens CCM 1774: purification and properties
J. Basic Microbiol.
28
25-33
1988
Acetobacter pasteurianus, Acetobacter pasteurianus CCM 1774
-
Manually annotated by BRENDA team
Aurich, H.; Sorger, H.; Bergmann, R.; Lasch, J.
Kinetics of membrane-bound aldehyde dehydrogenase from Acinetobacter calcoaceticus
Biol. Chem. Hoppe-Seyler
368
101-109
1987
Acinetobacter calcoaceticus
Manually annotated by BRENDA team
Aurich, H.; Sorger, H.; Bergmann, R.; Lasch, J.; Koelsch, R.
Wechselwirkungen der Aldehyddehydrogenase aus Acinetobacter calcoaceticus mit Membranlipiden. 1. Einflu¯ von Detergentien, Proteinasen und Phospholipasen auf die Solubilisierung und Aktivitaet des Enzyms
J. Basic Microbiol.
25
623-629
1985
Acinetobacter calcoaceticus
-
Manually annotated by BRENDA team
Aurich, H.; Bergmann, R.; Lasch, J.; Koelsch, R.; Sorger, H.
Wechselwirkungen der Aldehyddehydrogenase aus Acinetobacter calcoaceticus mit Membranlipiden. 2. Rekonstitution in kuenstlichen Membranvesikeln
J. Basic Microbiol.
25
631-636
1985
Acinetobacter calcoaceticus
-
Manually annotated by BRENDA team
Sasaki, S.; Sugawara, Y.
Aldehyde dehydrogenase from Proteus vulgaris
Methods Enzymol.
89
480-483
1982
Proteus vulgaris
Manually annotated by BRENDA team
Muraoka, H.; Watabe, Y.; Ogasawara, N.; Takahashi, H.
Purification and properties of five NADP-dependent aldehyde dehydrogenases from Acetobacter aceti
J. Ferment. Technol.
58
501-507
1980
Acetobacter aceti
-
Manually annotated by BRENDA team
Adachi, O.; Matsushita, K.; Shinagawa, E.; Ameyama, M.
Crystallization and properties of NADP-dependent aldehyde dehydrogenase from Gluconobacter melanogenus
Agric. Biol. Chem.
44
155-164
1980
Acetobacter aceti, Acetobacter acetigenus, Acetobacter orleanensis, Acetobacter ascendens, Frateuria aurantia, Gluconobacter oxydans, Acetobacter pasteurianus, Gluconobacter albidus, Gluconobacter cerinus, Gluconobacter gluconicus, Gluconacetobacter liquefaciens, Gluconobacter roseus, Gluconobacter sphaericus
-
Manually annotated by BRENDA team
Sugawara, Y.; Sasaki, S.
Purification and properties of aldehyde dehydrogenase from Proteus vulgaris
Biochim. Biophys. Acta
480
343-350
1977
Proteus vulgaris
Manually annotated by BRENDA team
Seegmiller, J.E.
Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast
J. Biol. Chem.
201
629-637
1953
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Jacobson, M.K.; Bernofsky, C.
Mitochondrial acetaldehyde dehydrogenase from Saccharomyces cerevisiae
Biochim. Biophys. Acta
350
277-291
1974
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Dickinson, F.M.
The purification and some properties of the Mg(2+)-activated cytosolic aldehyde dehydrogenase of Saccharomyces cerevisiae
Biochem. J.
315
393-399
1996
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ho, K.K.; Weiner, H.
Isolation and characterization of an aldehyde dehydrogenase encoded by the aldB gene of Escherichia coli
J. Bacteriol.
187
1067-1073
2005
Escherichia coli
Manually annotated by BRENDA team
Estey, T.; Piatigorsky, J.; Lassen, N.; Vasiliou, V.
ALDH3A1: a corneal crystallin with diverse functions
Exp. Eye Res.
84
3-12
2007
Oryctolagus cuniculus, Homo sapiens, Mammalia, Mus musculus
Manually annotated by BRENDA team
Short, D.M.; Lyon, R.; Watson, D.G.; Barski, O.A.; McGarvie, G.; Ellis, E.M.
Metabolism of trans, trans-muconaldehyde, acytotoxic metabolite of benzene, in mouse liver by alcohol dehydrogenase Adh1 and aldehyde reductase AKR1A4
Toxicol. Appl. Pharmacol.
210
163-170
2006
Mus musculus (Q540D7)
Manually annotated by BRENDA team
Lassen, N.; Bateman, J.B.; Estey, T.; Kuszak, J.R.; Nees, D.W.; Piatigorsky, J.; Duester, G.; Day, B.J.; Huang, J.; Hines, L.M.; Vasiliou, V.
Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice
J. Biol. Chem.
282
25668-25676
2007
Mus musculus
Manually annotated by BRENDA team
Patel, M.; Lu, L.; Zander, D.S.; Sreerama, L.; Coco, D.; Moreb, J.S.
ALDH1A1 and ALDH3A1 expression in lung cancers: correlation with histologic type and potential precursors
Lung Cancer
59
340-349
2008
Homo sapiens
Manually annotated by BRENDA team
Alka, K.; Ryan, B.J.; Dolly, J.O.; Henehan, G.T.
Substrate profiling and aldehyde dismutase activity of the Kvbeta2 subunit of the mammalian Kv1 potassium channel
Int. J. Biochem. Cell Biol.
42
2012-2018
2010
Rattus norvegicus
Manually annotated by BRENDA team
Mihasan, M.; Stefan, M.; Hritcu, L.; Artenie, V.; Brandsch, R.
Evidence of a plasmid-encoded oxidative xylose-catabolic pathway in Arthrobacter nicotinovorans pAO1
Res. Microbiol.
164
22-30
2013
Paenarthrobacter nicotinovorans
Manually annotated by BRENDA team
Mukhopadhyay, A.; Wei, B.; Weiner, H.
Mitochondrial NAD dependent aldehyde dehydrogenase either from yeast or human replaces yeast cytoplasmic NADP dependent aldehyde dehydrogenase for the aerobic growth of yeast on ethanol
Biochim. Biophys. Acta
1830
3391-3398
2013
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Bezsudnova, E.Y.; Petrova, T.E.; Artemova, N.V.; Boyko, K.M.; Shabalin, I.G.; Rakitina, T.V.; Polyakov, K.M.; Popov, V.O.
NADP-dependent aldehyde dehydrogenase from archaeon Pyrobaculum sp.1860: structural and functional features
Archaea
2016
9127857
2016
Pyrobaculum ferrireducens (G7VCG0), Pyrobaculum ferrireducens 1860 (G7VCG0)
Manually annotated by BRENDA team