1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase

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For detailed information about 4-trimethylammoniobutyraldehyde dehydrogenase, go to the full flat file.

Reaction

Synonyms

4-N-trimethylaminobutyraldehyde dehydrogenase, 4-N-trimethylaminobutyraldehyde dehydrogenase II, 4-trimethylaminobutyraldehyde dehydrogenase, 4-trimethylammoniobutyraldehyde dehydrogenase, aldehyde dehydrogenase 9A1, Aldh9a1, carnitine biosynthesis enzyme, dehydrogenase, trimethylaminobutyraldehyde, gamma-trimethylaminobutyraldehyde dehydrogenase, TMABA dehydrogenase, TMABA-DH, TMABADH, TMABAL dehydrogenase, TMABaldehyde-DH II, TMABALDH

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase

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Results	in table
1	Activating Compound
30	AA Sequence
1	Application
1	CAS Registry Number
5	Cloned(Commentary)
16	Cofactor
2	Crystallization (Commentary)
9	Disease/ Diagnostics
3	Expression
6	General Information
1	General Stability
44	Inhibitors
5	Ki Value [mM]
36	KM Value [mM]
8	Localization
1	Metals/Ions
9	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
19	Organism
5	Pathway
30	PDB ID
6	pH Optimum
1	pH Range
2	pH Stability
2	pI Value
7	Purification (Commentary)
1	Reaction
4	Reaction Type
18	Reference
54	Source Tissue
16	Specific Activity [micromol/min/mg]
3	Storage Stability
69	Substrates and Products (Substrate)
11	Subunits
36	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
3	Temperature Stability [°C]

General Stability

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General Stability on EC 1.2.1.47 - 4-trimethylammoniobutyraldehyde dehydrogenase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

the enzyme is very sensitive and becomes nearly inactive after two re-freezing cycles. The highest melting temperatures are observed in buffers at pH 7.0 and 7.5

Homo sapiens

P49189

762831