1.2.1.52: oxoglutarate dehydrogenase (NADP+)

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For detailed information about oxoglutarate dehydrogenase (NADP+), go to the full flat file.

Reaction

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.52 oxoglutarate dehydrogenase (NADP+)

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Results	in table
9	AA Sequence
1	CAS Registry Number
8	Cofactor
3	KM Value [mM]
3	Natural Substrates/ Products (Substrates)
3	Organism
1	pH Optimum
1	Purification (Commentary)
1	Reaction
3	Reaction Type
3	Reference
3	Substrates and Products (Substrate)
1	Systematic Name

Substrates Products

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Substrates Products on EC 1.2.1.52 - oxoglutarate dehydrogenase (NADP+)

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

2-oxoglutarate + CoA + NADP+

succinyl-CoA + CO2 + NADPH

3 entries

2-oxoglutarate + CoA + NADP+

succinyl-CoA + CO2 + NADPH

Euglena gracilis

-

NAD+ has 20% activity of NADP+

288283

-

-

?

2-oxoglutarate + CoA + NADP+

succinyl-CoA + CO2 + NADPH

Pseudomonas sp.

-

-

288287

-

-

?

2-oxoglutarate + CoA + NADP+

succinyl-CoA + CO2 + NADPH

Pseudomonas sp.

-

NAD+ has 4% reactivity of NADP+

288285

-

-

?