1.2.1.58: phenylglyoxylate dehydrogenase (acylating)

This is an abbreviated version!
For detailed information about phenylglyoxylate dehydrogenase (acylating), go to the full flat file.

Reaction

phenylglyoxylate
+
NAD+
+
CoA
=
benzoyl-S-CoA
+
CO2
+
NADH

Synonyms

Dehydrogenase, phenylglyoxylate (CoA-benzoylating), Phenylglyoxal:NAD+ oxidoreductase (CoA benzoylating), Phenylglyoxylate dehydrogenase (CoA benzoylating), Phenylglyoxylate-acceptor oxidoreductase, Phenylglyoxylate:acceptor oxidoreductase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.58 phenylglyoxylate dehydrogenase (acylating)

Systematic Name

Systematic Name on EC 1.2.1.58 - phenylglyoxylate dehydrogenase (acylating)

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SYSTEMATIC NAME
IUBMB Comments
phenylglyoxylate:NAD+ oxidoreductase
Requires thiamine diphosphate as cofactor. The enzyme from the denitrifying bacterium Azoarcus evansii is specific for phenylglyoxylate. 2-Oxoisovalerate is oxidized at 15% of the rate for phenylglyoxylate. Also reduces viologen dyes. Contains iron-sulfur centres and FAD.