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1.2.1.59: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

This is an abbreviated version!
For detailed information about glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating), go to the full flat file.

Word Map on EC 1.2.1.59

Reaction

D-glyceraldehyde 3-phosphate
+
phosphate
 +
NAD(P)+
=
3-phospho-D-glyceroyl phosphate
 +
NAD(P)H
 +
H+

Synonyms

cgap, chloroplast glyceraldehyde-3-phosphate dehydrogenase, CjGAPDH, Dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide (phosphate)), GAP, GapA, GapB, GAPC, GAPDH, GAPDH2, GBS GAPDH, glyceraldehyde 3-phosphate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)), NAD(NADP)-dependent glyceraldehyde-3-phosphate dehydrogenase, NAD(P)-dependent G3P dehydrogenase, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent glyceraldehyde 3-phosphate dehydrogenase, NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent glyceraldehydephosphate dehydrogenase, pcal_0632, phosphorylating glyceraldehyde-3-phosphate dehydrogenase, STK_13560, Triosephosphate dehydrogenase (NAD(P)), Tsac_2486

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

Cloned

Cloned on EC 1.2.1.59 - glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
cloned by functional complementation of an Escherichia coli gap mutant
-
expressed in Escherichia coli Rosetta DE3 cells
-
expressed in phosphoglucose isomerase-disrupted Escherichia coli (KS002) cells
expression at high levels in Escherichia coli, the primary structure exhibits a strikingly high proportion of aromatic amino acids
-
expression in Escherichia coli
gene gap, phylogenetic analysis and tree, recombinant expression in Escherichia coli strain BL21-CodonPlus (DE3)-RIL
gene gapA, recombinant overexpression of mutant enzymes in Escherichia coli strain BL21(DE3)
gene gapC, recombinant overexpression in Corynebacterium glutamicum strain ATCC 13032, coexpression with Bacillus subtilis gene rocG encoding NAD+-dependent glutamate dehydrogenase, leading to increased L-ornithine biosynthesis in the engineered strain, overview. Quantitative real-time PCR expression analysis. Effects of overexpression of genes encoding enzymes in the upstream pathway of glutamate biosynthesis on L-ornithine production in Corynebacterium glutamicum DELTAAP. Overexpression of Clostridium acetobutylicum gapC increases the production of CoQ10
gene gapdh, recombinant expression of the Thermoanaerobacterium saccharolyticum Gapdh in Clostridium thermocellum
recombinant expression of N-terminal His6-tagged enzyme in Escherichia coli strain BL21(DE3)pLysS Rosetta