1.2.1.90: glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

D-glyceraldehyde 3-phosphate
+
NAD(P)+
+
H2O
=
3-phospho-D-glycerate
+
NAD(P)H
+ 2 H+

Synonyms

GAPN, NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase, NAD+-dependent non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase, non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase, nonphosphorylating NAD+-dependent GAPN

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

Crystallization

Crystallization on EC 1.2.1.90 - glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
hanging drop vapor diffusion method. Crystal structure of of the complex of the enzyme with its natural inhibitor NADP+. The structure is solved by multiple anomalous diffraction and refined to a resolution of 2.4 A with a crystallographic R-factor of 0.21
hanging-drop vapour-diffusion method, crystal structure of the enzyme in complex with the substrate D-glyceraldehyde 3-phosphate at 2.3 A resolution, crystal structure of the enzyme in complex with NAD+ at 2.2 A resolution, co-crystal structures with the activating molecules glucose 1-phosphate, fructose 6-phosphate, AMP and ADP determined at resolutions ranging from 2.3 A to 2.6 A