1.2.1.99: 4-(gamma-glutamylamino)butanal dehydrogenase

This is an abbreviated version!
For detailed information about 4-(gamma-glutamylamino)butanal dehydrogenase, go to the full flat file.

Reaction

Synonyms

ALDH, gamma-Glu-gamma-aminobutyraldehyde dehydrogenase, gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [NAD(P)+], NAD+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase, PuuC

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase

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Results	in table
5	Activating Compound
1	AA Sequence
6	Application
5	Cloned(Commentary)
3	Cofactor
1	General Information
27	Inhibitors
13	kcat/KM [mM/s]
13	KM Value [mM]
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
17	Organism
5	Pathway
2	pH Optimum
2	pH Range
3	Purification (Commentary)
1	Reaction
9	Reference
16	Specific Activity [micromol/min/mg]
27	Substrates and Products (Substrate)
2	Subunits
11	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]
13	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.2.1.99 - 4-(gamma-glutamylamino)butanal dehydrogenase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.3

Escherichia coli

P23883

Vmax: 3-hydroxypropionate, pH 8.0, 37°C, cofactor: NADH

690591

1.5

Klebsiella pneumoniae

-

recombinant KpBC_DELTA_dhaT_DELTA_yqhD strain, pH 8.0, 45°C

724621

12.39

Escherichia coli

P23883

Vmax: acetaldehyde, pH 8.0, 37°C, cofactor: NAD+

690591

19.51

Escherichia coli

P23883

Vmax: benzaldehyde, pH 8.0, 37°C, cofactor: NAD+

690591

2.5

Klebsiella pneumoniae

-

recombinant KpC_DELTA_dhaT_DELTA_yqhD strain, pH 8.0, 45°C

724621

22.25

Klebsiella pneumoniae

-

Vmax: 3-hydroxypropionaldehyde, pH 8.0, 45°C

711536

27.35

Escherichia coli

P23883

Vmax: propionaldehyde, pH 8.0, 37°C, cofactor: NAD+

690591

28.61

Klebsiella pneumoniae

-

Vmax: isovaleraldehyde, pH 8.0, 45°C

711536

29.47

Escherichia coli

P23883

Vmax: valeraldehyde, pH 8.0, 37°C, cofactor: NAD+

690591

30.07

Escherichia coli

P23883

Vmax: butyraldehyde, pH 8.0, 37°C, cofactor: NAD+

690591

30.67

Escherichia coli

P23883

Vmax: isovaleraldehyde, pH 8.0, 37°C, cofactor: NAD+

690591

32.1

Escherichia coli

P23883

Vmax: 3-hydroxypropionaldehyde, pH 8.0, 37°C, cofactor: NAD+

690591

33.26

Klebsiella pneumoniae

-

Vmax: valeraldehyde, pH 8.0, 45°C

711536

34.08

Klebsiella pneumoniae

-

Vmax: butyraldehyde, pH 8.0, 45°C

711536

5.5

Escherichia coli

P23883

Vmax: 3-hydroxypropionaldehyde, pH 8.0, 37°C, cofactor: NADP+

690591

additional information

Klebsiella pneumoniae

-

activity varies depending on the type of strain and culture conditions, e.g. aeration conditions and working volume

724621