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1.2.3.3: pyruvate oxidase

This is an abbreviated version!
For detailed information about pyruvate oxidase, go to the full flat file.

Word Map on EC 1.2.3.3

Reaction

pyruvate
+
phosphate
+
O2
=
acetyl phosphate
+
CO2
+
H2O2

Synonyms

acetyl phosphate-producing pyruvate oxidase, phosphate-dependent pyruvate oxidase, POD, POX, POX-2, poxB, PoxF, PyOD, PyrOx, pyruvate oxidase, pyruvate:oxygen-2-oxidoreductase (phosphorylating), pyruvic oxidase, SpxB, SpxB protein

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.3 With oxygen as acceptor
                1.2.3.3 pyruvate oxidase

Substrates Products

Substrates Products on EC 1.2.3.3 - pyruvate oxidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2 pyruvate + phosphate + 2 O2 + H2O
acetate + acetyl phosphate + 2 CO2 + 2 H2O2
show the reaction diagram
acetaldehyde + phosphate + O2 + H2O
? + H2O2
show the reaction diagram
-
15% of the activity compared to pyruvate as substrate
-
?
alpha-ketobutyrate + phosphate + O2 + H2O
? + H2O2
show the reaction diagram
-
very low activity
-
?
methylglyoxal + phosphate + O2 + H2O
? + H2O2
show the reaction diagram
-
20% of the activity compared to pyruvate as substrate
-
?
pyruvate + arsenate + O2 + H2O
acetyl arsenate + CO2 + H2O2
show the reaction diagram
-
can replace phosphate, 25% higher activity compared to phosphate as cosubstrate
-
?
pyruvate + H2O
acetate + CO2
show the reaction diagram
pyruvate + phosphate + 2,6-dichlorophenolindophenol + H2O
acetyl phosphate + CO2 + reduced 2,6-dichlorophenolindophenol + H2O2
show the reaction diagram
pyruvate + phosphate + ferricyanide + H2O
acetyl phosphate + ferrocyanide + H2O2
show the reaction diagram
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
show the reaction diagram
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
show the reaction diagram
additional information
?
-