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1.2.3.6: pyruvate oxidase (CoA-acetylating)

This is an abbreviated version!
For detailed information about pyruvate oxidase (CoA-acetylating), go to the full flat file.

Reaction

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pyruvate
+
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CoA
+
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O2
=
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acetyl-CoA
+
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CO2
+
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H2O2

Synonyms

pyruvate oxidase, SpxB

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.3 With oxygen as acceptor
                EC 1.2.3.61.2.3.6 pyruvate oxidase (CoA-acetylating)

Engineering

Engineering on EC 1.2.3.6 - pyruvate oxidase (CoA-acetylating)

for references in articles please use BRENDA:EC1.2.3.6

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
G389D
-
spxB2 mutant, reduces H2O2 production to approximately that of a DELTAspxB null mutant. SpxB2 mutant shows an opaque colony phenotype and decreased production of H2O2
P449L
-
spxB4 mutant, reduces H2O2 production to approximately that of a DELTAspxB null mutant. SpxB4 mutant shows an opaque colony phenotype and decreased production of H2O2
additional information