1.2.99.6: carboxylate reductase

This is an abbreviated version!
For detailed information about carboxylate reductase, go to the full flat file.

Word Map on EC 1.2.99.6

Reaction

an aldehyde
+
acceptor
+
H2O
=
a carboxylate
+
reduced acceptor

Synonyms

aldehyde ferredoxin oxidoreductase, aldehyde oxidoreductase, aldehyde reductase, AOR, BV-AIDH, Carboxylic acid reductase, Carboxylic acid reductase/aldehyde reductase, Reductase, carboxylate, W-AOR

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.99 With unknown physiological acceptors
                1.2.99.6 carboxylate reductase

KM Value

KM Value on EC 1.2.99.6 - carboxylate reductase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
10
3,5-dimethoxy-4-hydroxybenzaldehyde
-
with carbamoyl methyl viologen as cosubstrate
2.4 - 3.8
3-chlorobenzoate
3.5
3-Fluorobenzoate
-
with reduced carbamoyl methyl viologen as cosubstrate
50.4 - 78
3-hydroxybenzoate
44.9
3-Methoxybenzoate
-
-
6.1 - 12.8
3-methylbenzoate
8
4-(hydroxymethyl)benzoate
-
with reduced carbamoyl methyl viologen as cosubstrate
1 - 1.2
4-Chlorobenzoate
1.4
4-Fluorobenzoate
-
-
3
4-hydroxy-3-methoxybenzaldehyde
-
4-methylbenzoate, with reduced carbamoyl methyl viologen as cosubstrate; with carbamoyl methyl viologen as cosubstrate
12
4-hydroxybenzaldehyde
-
with carbamoyl methyl viologen as cosubstrate
130 - 382
4-hydroxybenzoate
0.005
4-methoxybenzaldehyde
-
terephthalaldehyde, with carbamoyl methyl viologen as cosubstrate; with carbamoyl methyl viologen as cosubstrate
2.1
4-Methoxybenzoate
-
-
5
4-Methylbenzoate
-
-
0.1
5-Phenyl-2,4-pentadienate
-
with reduced carbamoyl methyl viologen as cosubstrate
0.0125 - 0.019
acetaldehyde
1.8 - 5.6
acetate
0.0014 - 0.057
benzaldehyde
16.7 - 53
Benzoate
0.169 - 0.55
benzyl viologen
0.002 - 0.022
Butanal
0.8
Butanoate
-
-
0.012
Butyraldehyde
-
-
0.012
cinnamaldehyde
-
with carbamoyl methyl viologen as cosubstrate
1.7
cinnamate
-
with reduced carbamoyl methyl viologen as cosubstrate
0.04 - 0.136
crotonaldehyde
0.016
DL-glyceraldehyde
-
-
0.01
ES-1 ferredoxin
-
0.0308
furfural
-
with benzyl viologen as cosubstrate
0.084
Glutaraldehyde
-
-
0.196
glyceraldehyde
-
with benzyl viologen as cosubstrate, at 45°C
0.05
Indoleacetaldehyde
0.028 - 0.033
Isovaleraldehyde
1.422 - 1.6
methanal
2.9
methyl viologen
0.067 - 0.076
phenylacetaldehyde
0.0055 - 0.15
propanal
6.3 - 6.4
propanoate
0.017
propionaldehyde
-
-
0.03 - 0.16
reduced carbamoyl methyl viologen
0.065
Salicylaldehyde
-
with benzyl viologen as cosubstrate, at 85°C
4
terephthalate
-
with reduced carbamoyl methyl viologen as cosubstrate