1.2.99.7: aldehyde dehydrogenase (FAD-independent)
This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (FAD-independent), go to the full flat file.
Word Map on EC 1.2.99.7
Reaction
Synonyms
aldehyde oxidase, aldehyde oxidoreductase, AOR, AORDd, BV-AIDH, DgAOR, MOP, MOP molybdenum-containing protein
ECTree
1.2.99.7 aldehyde dehydrogenase (FAD-independent)Advanced search results
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results (Substrates Products
Substrates Products on EC 1.2.99.7 - aldehyde dehydrogenase (FAD-independent)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2,3-dihydroxybenzaldehyde + H2O + 2,6-dichlorophenol-indophenol
2,3-dihydroxybenzoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
2,5-dihydroxybenzaldehyde + H2O + 2,6-dichlorophenol-indophenol
2,5-dihydroxybenzoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
2-hydroxybenzaldehyde + H2O + phenyazine methosulfate
2-hydroxybenzylic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
2-nitrobenzaldehyde + H2O + phenyazine methosulfate
2-nitrobenzylic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
2-phenylacetaldehyde + H2O + 2,6-dichlorophenol-indophenol
2-phenylacetate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
3-(benzyloxy)-4-oxo-4H-pyran-2-carbaldehyde + H2O + phenyazine methosulfate
3-(benzyloxy)-4-oxo-4H-pyran-2-carboxylic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
3-hydroxybenzaldehyde + H2O + 2,6-dichlorophenol-indophenol
3-hydroxybenzoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
3-hydroxybenzaldehyde + H2O + phenyazine methosulfate
3-hydroxybenzylic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
3-nitrobenzaldehyde + H2O + phenyazine methosulfate
3-nitrobenzylic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
3-phenylpropanal + H2O + 2,6-dichlorophenol-indophenol
3-phenylpropanoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
3-pyridinecarboxaldehyde + H2O + 2,6-dichlorophenol-indophenol
3-pyridinecarboxylate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
159% of activity with acetaldehyde
-
-
?
4-hydroxybenzaldehyde + H2O + phenyazine methosulfate
4-hydroxybenzylic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
4-nitrobenzaldehyde + H2O + phenyazine methosulfate
4-nitrobenzoic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
acetaldehyde + H2O + 2,6-dichlorophenol-indophenol
acetate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
-
?
acetaldehyde + H2O + 2,6-dichlorophenolindophenol
acetate + reduced 2,6-dichlorophenolindophenol
Megalodesulfovibrio gigas
-
-
-
-
?
acetaldehyde + H2O + benzylviologen
acetate + reduced benzylviologen
Megalodesulfovibrio gigas
-
natural electron aceptor not yet known, the artificial electron acceptors benzylviologen, methylviologen, 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl) and 2,6-dichlorphenol-indophenol have relative activities of 100%, 19%, 5%, and 1.3%, respectively
-
-
?
acetaldehyde + H2O + electron acceptor
acetate + reduced acceptor
Megalodesulfovibrio gigas
-
-
-
-
?
benzaldehyde + 2 ferricyanide + H2O
benzoate + 2 ferrocyanide + 2 H+
Megalodesulfovibrio gigas
-
156% of activity with 2,6-dichlorophenol-indophenol
-
-
?
benzaldehyde + H2O + 2,6-dichlorophenol-indophenol
benzoate + reduced 2,6-dichlorophenol-indophenol
benzaldehyde + H2O + 2,6-dichlorophenolindophenol
benzoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
benzaldehyde + H2O + 2,6-dichlorophenolindophenol
benzoate + reduced 2,6-dichlorophenolindophenol
benzaldehyde + H2O + cytochrome c
benzoate + reduced cytochrome c
Megalodesulfovibrio gigas
-
from horse heart, 25% of activity with 2,6-dichlorophenol-indophenol
-
-
?
benzaldehyde + H2O + cytochrome c3
benzoate + reduced cytochrome c3
Megalodesulfovibrio gigas
-
from, Desulfovibrio gigas, 20% of activity with 2,6-dichlorophenol-indophenol
-
-
?
benzaldehyde + H2O + electron acceptor
benzoate + reduced electron acceptor
Megalodesulfovibrio gigas
-
-
-
-
?
benzaldehyde + H2O + methylene blue
benzoate + reduced methylene blue
Megalodesulfovibrio gigas
-
156% of activity with 2,6-dichlorophenol-indophenol
-
-
?
benzaldehyde + H2O + oxidized 2,6-dichlorophenolindophenol
benzoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
-
?
benzaldehyde + H2O + phenyazine methosulfate
benzylic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
butyraldehyde + H2O + benzylviologen
butanoate + reduced benzylviologen
Megalodesulfovibrio gigas
-
93% of activity with acetaldehyde
-
-
?
cinnamaldehyde + H2O + 2,6-dichlorophenol-indophenol
cinnamate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
cinnamaldehyde + H2O + phenyazine methosulfate
cinnamic acid + reduced phenyazine methosulfate
A0A5K7VLU0; A0A5K7VFT8
-
-
-
?
formaldehyde + H2O + benzylviologen
formate + reduced benzylviologen
Megalodesulfovibrio gigas
-
16% of activity with acetaldehyde
-
-
?
furfural + H2O + benzylviologen
furfurate + reduced benzylviologen
Megalodesulfovibrio gigas
-
77% of activity with acetaldehyde
-
-
?
furfuraldehyde + H2O + 2,6-dichlorophenol-indophenol
furfurate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
27% of activity with acetaldehyde
-
-
?
glutaraldehyde + H2O + benzylviologen
glutarate + reduced benzylviologen
Megalodesulfovibrio gigas
-
20% of activity with acetaldehyde
-
-
?
glycoaldehyde + H2O + benzylviologen
glycolate + reduced benzylviologen
Megalodesulfovibrio gigas
-
23% of activity with acetaldehyde
-
-
?
hexanal + H2O + benzylviologen
hexanoate + reduced benzylviologen
Megalodesulfovibrio gigas
-
6% of activity with acetaldehyde
-
-
?
octanal + H2O + benzylviologen
octanoate + reduced benzylviologen
Megalodesulfovibrio gigas
-
93% of activity with acetaldehyde
-
-
?
p-anisaldehyde + H2O + benzylviologen
p-anisic acid + reduced benzylviologen
Megalodesulfovibrio gigas
-
5% of activity with acetaldehyde
-
-
?
pentanal + H2O + benzylviologen
pentanoate + reduced benzylviologen
Megalodesulfovibrio gigas
-
9% of activity with acetaldehyde
-
-
?
phenylacetaldehyde + H2O + benzylviologen
phenylacetate + reduced benzylviologen
Megalodesulfovibrio gigas
-
31% of activity with acetaldehyde
-
-
?
propionaldehyde + H2O + 2,6-dichlorophenol-indophenol
propionate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
-
?
propionaldehyde + H2O + 2,6-dichlorophenolindophenol
propionate + reduced 2,6-dichlorophenolindophenol
Megalodesulfovibrio gigas
-
-
-
-
?
propionaldehyde + H2O + benzylviologen
propionate + reduced benzylviologen
Megalodesulfovibrio gigas
-
117% of activity with acetaldehyde
-
-
?
salicylaldehyde + H2O + 2,6-dichlorophenol-indophenol
salicylate + reduced 2,6-dichlorophenol-indophenol
salicylaldehyde + H2O + 2,6-dichlorophenolindophenol
salicylate + reduced 2,6-dichlorophenolindophenol
Megalodesulfovibrio gigas
-
-
-
-
?
salicylaldehyde + H2O + benzylviologen
salicylate + reduced benzylviologen
Megalodesulfovibrio gigas
-
14% of activity with acetaldehyde
-
-
?
acetaldehyde + H2O + acceptor
acetate + reduced acceptor
Megalodesulfovibrio gigas
-
aldehyde oxidoreductase does not react with O2
-
-
?
acetaldehyde + H2O + electron acceptor
acetate + reduced electron acceptor
Megalodesulfovibrio gigas
-
-
-
-
?
acetaldehyde + H2O + electron acceptor
acetate + reduced electron acceptor
Megalodesulfovibrio gigas
-
DgAOR probably reduces aldehydes to alcohols
-
-
?
aldehyde + H2O + acceptor
carboxylate + reduced acceptor
Oleidesulfovibrio alaskensis
-
-
-
-
?
aldehyde + H2O + acceptor
carboxylate + reduced acceptor
Oleidesulfovibrio alaskensis NCIMB 1349
-
-
-
-
?
aldehyde + H2O + acceptor
carboxylate + reduced acceptor
Oleidesulfovibrio alaskensis NCIMB 13491
-
-
-
-
?
benzaldehyde + H2O + 2,6-dichlorophenol-indophenol
benzoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
-
?
benzaldehyde + H2O + 2,6-dichlorophenol-indophenol
benzoate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
benzaldehyde + H2O + 2,6-dichlorophenolindophenol
benzoate + reduced 2,6-dichlorophenolindophenol
Oleidesulfovibrio alaskensis
-
-
-
-
?
benzaldehyde + H2O + 2,6-dichlorophenolindophenol
benzoate + reduced 2,6-dichlorophenolindophenol
Oleidesulfovibrio alaskensis NCIMB 1349
-
-
-
-
?
benzaldehyde + H2O + 2,6-dichlorophenolindophenol
benzoate + reduced 2,6-dichlorophenolindophenol
Oleidesulfovibrio alaskensis NCIMB 13491
-
-
-
-
?
benzaldehyde + H2O + benzylviologen
benzoate + reduced benzylviologen
Megalodesulfovibrio gigas
-
16% of activity with acetaldehyde
-
-
?
benzaldehyde + H2O + benzylviologen
benzoate + reduced benzylviologen
Megalodesulfovibrio gigas
-
93% of activity with acetaldehyde
-
-
?
salicylaldehyde + H2O + 2,6-dichlorophenol-indophenol
salicylate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
-
?
salicylaldehyde + H2O + 2,6-dichlorophenol-indophenol
salicylate + reduced 2,6-dichlorophenol-indophenol
Megalodesulfovibrio gigas
-
-
-
?
additional information
?
-
Megalodesulfovibrio gigas
-
the enzyme also catalyzes the nitrite reduction with nitric oxide formation in an enzyme-, aldehyde- and nitrite-concentration- dependent manner. The enzyme catalyzes the nitrite reduction to nitric oxide in the presence of an electron donor to the enzyme, substrate (aldehyde) or not (dithionite)
-
-
?
additional information
?
-
Megalodesulfovibrio gigas
no substrates: hypoxanthine, xanthine, 1-methylxanthine, 3-methylxanthine, 1,3,7-trimethylxanthine, allopurinol, oxypurinol, isoquinoline, nicotinate, formamide
-
-
?
additional information
?
-
A0A5K7VLU0; A0A5K7VFT8
additional albeit significantly less effective acdeptors are dichlorophenolindophenol, methylene blue, ferricyanide
-
-
-
