1.3.1.10: enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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For detailed information about enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific), go to the full flat file.

Word Map on EC 1.3.1.10

1.3.1.10

tuberculosis

mycobacterium

triclosan

isoniazid

aureus

falciparum

antitubercular

polyketide

mycolic

beta-ketoacyl

thioesterase

pfenr

antimycobacterial

diphenyl

antituberculosis

diazaborine

fas-ii

ketoacyl

dehydrase

biocide

anti-tb

malonyl

ketoreductase

transacylase

beta-ketoacyl-acp

catalase-peroxidase

mdr-tb

drug development

Reaction

trans-2,3-dehydroacyl-[acyl-carrier protein]

Synonyms

1-cyclohexenylcarbonyl coenzyme A reductase, 2-enoyl thioester reductase, 2-trans-enoyl-ACP reductase, acyl-ACP dehydrogenase, beta-ketoacyl reductase, enoyl acyl-carrier-protein reductase, enoyl reductase, enoyl thioester reductase, enoyl-ACP reductase, enoyl-ACP reductase II, enoyl-ACP reductase III, enoyl-ACP-reductase II, enoyl-acyl carrier protein reductase, enoyl-[acyl carrier protein] reductase, enoyl-[acyl-carrier-protein] reductase, ENR, Etr1p, fabG4, FabI, FabK, FabL, Fabl2, More, Mrf1p, NADPH 2-enoyl Co A reductase, reductase, enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate), trans-enoyl-[acyl-carrier-protein] reductase, YgaA

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.1 With NAD⁺ or NADP⁺ as acceptor

1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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Results	in table
1	Activating Compound
679	AA Sequence
1	Application
2	CAS Registry Number
15	Cloned(Commentary)
25	Cofactor
5	Crystallization (Commentary)
1	Expression
5	General Information
1	General Stability
3	IC50 Value
21	Inhibitors
6	Ki Value [mM]
23	KM Value [mM]
3	Localization
9	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
160	Organism
12	Pathway
225	PDB ID
5	pH Optimum
2	pH Range
2	pH Stability
25	Protein Variants
16	Purification (Commentary)
3	Reaction
3	Reaction Type
36	Reference
12	Specific Activity [micromol/min/mg]
3	Storage Stability
80	Substrates and Products (Substrate)
12	Subunits
61	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Stability [°C]
11	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.3.1.10 - enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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1-cyclohexenylcarbonyl-CoA + NADPH

1-cyclohexylcarbonyl-CoA + NADP+

Streptomyces collinus

reaction in ansatrienin biosynthesis out of shikimic acid

390509

5-hydroxycyclohex-1-enecarbonyl-CoA + NADPH

5-hydroxycyclohexylcarbonyl-CoA + NADP+

Streptomyces collinus

reaction in ansatrienin biosynthesis out of shikimic acid

390509

an acyl-[acyl-carrier protein] + NADP+

a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+

3 entries

beta-ketoacyl-[acyl-carrier protein] + NADH + H+

beta-hydroxyacyl-[acyl-carrier protein] + NAD+

Mycobacterium tuberculosis

740013

trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH

acyl-[acyl-carrier protein] + NADP+

2 entries

trans-3,4-dihydroxycyclohexa-1,5-dienecarbonyl-CoA + NADPH

trans-4,5-dihydroxycyclohexa-2-enecarbonyl-CoA + NADP+

Streptomyces collinus

reaction in ansatrienin biosynthesis out of shikimic acid

390509

additional information

22 entries