1.3.1.100: chanoclavine-I aldehyde reductase

This is an abbreviated version!
For detailed information about chanoclavine-I aldehyde reductase, go to the full flat file.

Reaction

Synonyms

EasA, FgaOx3, FgaOx3Pr3, old yellow enzyme

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.100 chanoclavine-I aldehyde reductase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

All data fields related to EC 1.3.1.100

Results	in table
4	AA Sequence
5	Cloned(Commentary)
11	Cofactor
1	Crystallization (Commentary)
4	General Information
2	KM Value [mM]
2	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
15	Organism
3	Pathway
1	PDB ID
5	Purification (Commentary)
1	Reaction
13	Reference
10	Substrates and Products (Substrate)
4	Subunits
18	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

Systematic Name

Systematic Name on EC 1.3.1.100 - chanoclavine-I aldehyde reductase

for references in articles please use BRENDA:EC1.3.1.100

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

chanoclavine-I aldehyde:NAD+ oxidoreductase

Contains FMN. The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid produced by some fungi of the Trichocomaceae family. The enzyme catalyses the reduction of chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde. This hydrolyses spontaneously to form 6,8-dimethyl-6,7-didehydroergoline, which is converted to festuclavine by EC 1.5.1.44, festuclavine dehydrogenase.