1.3.1.101: 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
This is an abbreviated version!
For detailed information about 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H], go to the full flat file.
Reaction
+ 8 NAD(P)+ = + 8 NAD(P)H + 8 H+
Synonyms
2,3-digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, digeranylgeranylglycerophospholipid reductase, Ta0516m
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.3.1.101 - 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
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REACTION DIAGRAM
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
2,3-bis-O-geranylgeranyl-sn-glyceryl 1-phosphate + 8 NAD(P)H + 8 H+
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
the enzyme catalyzes a critical step in the biosynthesis of archaeal membrane lipids. The saturation of hydrocarbon chains confers the ability to resist hydrolysis and oxidation and helps archaea withstand extreme conditions
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2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
formation of 2,3-di-O-phytanyl-sn-glyceryl phosphate (archaetidic acid), which is the basic core structure of archaeal membrane lipids
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2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
formation of 2,3-di-O-phytanylglyceryl phosphate, which is the basic core structure of archaeal membrane lipids
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